Results 41 to 50 of about 35,686 (231)

The Conundrum of Dedifferentiation in a Liposarcoma at a Peculiar Location: A Case Report and Literature Review

open access: yesMedicina, 2023
Dedifferentiated liposarcoma of the deep soft tissue of the lower extremities is an infrequent finding. Myxoid liposarcoma is considered the most common soft tissue neoplasia arising in this anatomic region.
Ana-Maria Ciongariu   +9 more
doaj   +1 more source

Therapy-induced senescence contributes to the efficacy of abemaciclib in patients with dedifferentiated liposarcoma

open access: yesClinical Cancer Research, 2023
STRUCTURED ABSTRACT Purpose: We conducted research on CDK4/6 inhibitors (CDK4/6i) simultaneously in the pre-clinical and clinical spaces to gain a deeper understanding of how senescence influences tumor growth in humans.
Caroline E. Gleason   +35 more
semanticscholar   +1 more source

Notch signaling regulates a metabolic switch through inhibiting PGC-1α and mitochondrial biogenesis in dedifferentiated liposarcoma

open access: yesOncogene, 2023
Human dedifferentiated liposarcoma (DDLPS) is a rare but lethal cancer with no driver mutations being identified, hampering the development of targeted therapies.
Pei-Chieh Tien   +4 more
semanticscholar   +1 more source

Recurrent metastatic retroperitoneal dedifferentiated liposarcoma: a case report and literature review

open access: yesBMC Urology, 2023
Background Retroperitoneal liposarcoma (RPLPS), a rare tumor, is often treated using surgical procedures as the first choice for treatment. However, there is no consensus on the scope of surgical resection.
Tu-ming Liao   +6 more
semanticscholar   +1 more source

A novel HMGA2::KITLG fusion in a dedifferentiated liposarcoma with amplification of MDM2 and HMGA2

open access: yesGenes, Chromosomes and Cancer, 2023
High‐mobility group AT‐hook 2 (HMGA2) is rearranged in various types of mesenchymal tumors, particularly lipomas. HMGA2 is also co‐amplified with mouse double minute 2 (MDM2) in well‐differentiated liposarcoma/dedifferentiated liposarcoma (WDLPS/DDLPS ...
Shishan Zhou   +8 more
semanticscholar   +1 more source

Dedifferentiated liposarcoma of the pyriform sinus [PDF]

open access: yes, 2006
SummaryThe authors presented a second reported case of dedifferentiated liposarcoma of the pyriform sinus in a 50-year old male, with a history of heavy smoking, airway obstruction and dysphagia. A computed tomography (CT) of the neck and thorax revealed
Ferri, Teore   +4 more
core   +3 more sources

Targeting the MDM2-p53 pathway in dedifferentiated liposarcoma

open access: yesFrontiers in Oncology, 2022
Dedifferentiated liposarcoma (DDLPS) is an aggressive adipogenic cancer with poor prognosis. DDLPS tumors are only modestly sensitive to chemotherapy and radiation, and there is a need for more effective therapies.
R. Traweek   +5 more
semanticscholar   +1 more source

Liposarcoma of stomach: report of a case [PDF]

open access: yes, 1968
A report is made on a case of liposarcoma of stomach in a 42 year old man. This is the first case of liposarcoma of stomach reported in Japan. The patient has remained asymptomatic for five years after operation.
Orita, Kunzo   +4 more
core   +1 more source

Cystic retroperitoneal dedifferentiated liposarcoma: A case report

open access: yesJournal of Clinical Imaging Science, 2023
Liposarcoma is the most common primary retroperitoneal sarcoma in adults. We report the case of an 86-year-old male who presented to the emergency department with frequent falls and unexplained weight loss that was found to have a cystic retroperitoneal ...
Sarah . Sorour   +3 more
semanticscholar   +1 more source

Giant retroperitoneal dedifferentiated liposarcoma mimicking ovarian cancer: A case report

open access: yesGynecologic Oncology Reports, 2022
Retroperitoneal liposarcoma is a rare tumor, and its dedifferentiated subtype and a larger diameter are associated with a poor prognosis. However, there are few reports of retroperitoneal liposarcomas, both with a dedifferentiated subtype and a diameter ...
Akihiro Tani   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy