Results 51 to 60 of about 4,421 (165)

Neoadjuvant chemotherapy for soft‐tissue sarcoma of the extremities: A post‐hoc Sarculator‐based risk analysis of the EORTC 62961–ESHO 95 randomized trial

open access: yesCancer, Volume 132, Issue 9, 1 May 2026.
Abstract Background In the EORTC 62961–ESHO 95 randomized trial (European Organization for Research and Treatment 62961–European Society of Hyperthermia Oncology 95; ClinicalTrials.gov identifier NCT00003052), neoadjuvant chemotherapy (NAC) combined with regional hyperthermia (RHT) improved survival in patients with soft tissue sarcoma (tumor size >5 ...
Markus Albertsmeier   +15 more
wiley   +1 more source

Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma

open access: yesClinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie   +21 more
wiley   +1 more source

Primary Diaphragmatic Dedifferentiated Liposarcoma in a Young Female Patient after Delivery

open access: yesCase Reports in Oncological Medicine, 2016
A 26-year-old woman was admitted with the chief complaint of chest pain. She had delivered her first child 9 months before admission. Computed tomography showed a bulky mass in her left chest, and histopathological analysis revealed it to be ...
Shinya Sakata   +5 more
doaj   +1 more source

Decoding the Hexosamine Biosynthesis Pathway: Implications for Novel Therapeutic Strategies in Sarcoma

open access: yesJournal of Cellular Physiology, Volume 241, Issue 5, May 2026.
ABSTRACT Cancer cells rewire their metabolism to sustain a high proliferation rate. Sensing external cues is essential to match the metabolic fluxes of the cells to the external stimuli. As part of the glucose metabolism, the hexosamine biosynthesis pathway (HBP) is considered a nutrient‐sensing pathway. The HBP produces UDP‐GlcNAc, a key precursor for
Pegah Rahimizadeh   +4 more
wiley   +1 more source

Dedifferentiated liposarcoma of the gallbladder [PDF]

open access: yesThe Kaohsiung Journal of Medical Sciences, 2020
Yung‐Tsung Cheng   +3 more
openaire   +3 more sources

Well‐Differentiated, Low‐Grade Subcutaneous Liposarcoma With a Fatal Outcome in a Dog

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This case report describes a rapidly growing subcutaneous liposarcoma with a fatal outcome in a 10‐year‐old intact male Rottweiler. The neoplasm was suspected cytologically and confirmed histologically. Despite its well‐differentiated, low‐grade features, the dog died within three months of diagnosis, highlighting the potential for metastasis of such ...
Peres Ramos Badial   +4 more
wiley   +1 more source

Primary dedifferentiated liposarcoma of the breast: A case report

open access: yesClinical Case Reports, 2022
Primary breast liposarcoma is an extraordinarily rare breast malignancy. Histological subtypes including dedifferentiated are confirmed after a thorough histopathological and immunohistochemistry analysis. Liposarcoma of the breast can mimic other breast
Suraj Shrestha   +5 more
doaj   +1 more source

A Case of Gastric Atypical Lipomatous Tumor/Well‐Differentiated Liposarcoma With Endoscopic Morphological Changes

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Atypical lipomatous tumor/well‐differentiated liposarcoma is a locally aggressive mesenchymal neoplasm composed of adipocytes and stromal cells. Gastric cases are exceedingly rare, and their malignant potential remains unclear. We report a case of a woman in her 60s who was found to have multiple submucosal tumor‐like lesions of the stomach ...
Rika Omote   +9 more
wiley   +1 more source

High dietary fiber is associated with improved outcomes in patients with melanoma and sarcoma treated with immunotherapy regardless of gut microbiome dysbiosis and social vulnerability

open access: yesCancer, Volume 132, Issue 6, 15 March 2026.
ABSTRACT Background Social vulnerability, dietary fiber, and the gut microbiome have been individually implicated in clinical outcomes for melanoma and sarcoma patients. This study hypothesized that increasing social vulnerability is associated with insufficient dietary fiber intake and negatively associated with microbiome composition and clinical ...
Brittany C. Fields   +15 more
wiley   +1 more source

Pattern and Clinical Significance of CA19‐9 Expression in Human Cancer: A Tissue Microarray Study on 14,966 Tumors

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Carbohydrate antigen 19–9 (CA19‐9) is a cell surface glycoprotein widely used as a diagnostic and prognostic serum marker for monitoring pancreatic cancer. The aim of this study was to evaluate the prevalence and clinical relevance of CA19‐9 expression in human cancer. Methods To comprehensively determine the prevalence and clinical
Nina Schraps   +31 more
wiley   +1 more source

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