Results 81 to 90 of about 35,686 (231)

A single-arm phase 2 trial of Sitravatinib in advanced well-differentiated/dedifferentiated liposarcoma.

Clinical Cancer Research, 2022
PURPOSE To evaluate Sitravatinib, an inhibitor of multiple receptor tyrosine kinases (RTKs), for the treatment of well-differentiated/dedifferentiated liposarcoma (WD/DD LPS).
M. Ingham, Shing M. Lee, B. Van Tine, E. Choy, Jay H. Oza, Sahil D. Doshi, Lin-Er Ge, P. Oppelt, G. Cote, B. Corgiat, Naomi Sender, Sarah Sta Ana, Lavan Panchalingam, E. Petricoin, G. Schwartz   +14 more
semanticscholar   +1 more source

Dedifferentiated liposarcoma of the left thigh: a rare case

, 2019
PubMed: 31391701Introduction: Liposarcoma is generally classified into four subtypes: a) well-differentiated liposarcoma/atypical lipomatous tumor, b) dedifferentiated liposarcoma, c) myxoid/round cell liposarcoma, and d) pleomorphic liposarcoma ...
Üstün, Hüseyin, engül, Demet, engül, lker   +2 more
core   +1 more source

Clear cell renal carcinoma synchronous with dedifferentiated liposarcoma: a case report and review of the literature

Journal of Medical Case Reports, 2020
Background Multiple primary malignant neoplasms are not frequent but are increasing in incidence. Some of them are associated with genetic syndromes such as von Hippel-Lindau syndrome and Li-Fraumeni syndrome.
Estefania Beltran, Juan Esteban Garcia-Robledo, Lisa X. Rodríguez-Rojas, Martin Rengifo, Bladimir Perez, Harry Pachajoa, Angela R. Zambrano   +6 more
doaj   +1 more source

Dedifferentiation in endometrial cancer is associated with HLA‐I silencing that may be restored by IFN‐γ

The Journal of Pathology, EarlyView.
Abstract Dedifferentiated endometrial carcinoma occurs when a prognostically favorable low‐grade endometrial carcinoma transforms into a highly aggressive undifferentiated carcinoma following genomic inactivation of core SWItch/Sucrose Non‐Fermentable (SWI/SNF) complex protein(s).
Antonio De Leo, Madison Wickenberg, Marco Grillini, Camelia Alexandra Coadǎ, Pooja Praveen Kumar, Annie Tong, James Key, Hannah Kim, Felix Kommoss, Mark Carey, Yangxin Fu, Claudio Ceccarelli, Giovanni Tallini, Paul LaPointe, Martin Köbel, Cheng‐Han Lee   +15 more
wiley   +1 more source

Retrospective evaluation of the role of gemcitabine‐docetaxel in well‐differentiated and dedifferentiated liposarcoma

Cancer Medicine, 2022
Well‐differentiated (WDLPS) and dedifferentiated liposarcoma (DDLPS) account for the majority of liposarcomas. Although gemcitabine‐docetaxel is used as second‐line treatment in soft tissue sarcomas, its efficacy in WDLPS/DDLPS is not established.
P. Thirasastr, Heather Y. Lin, B. Amini, Wei-Lien Wang, J. Cloutier, E. Nassif, E. Keung, C. Roland, B. Feig, D. Araujo, R. Benjamin, A. Conley, J. Livingston, J. Ludwig, Shreyaskumar R. Patel, R. Ratan, V. Ravi, M. Zarzour, Xiao Zhou, N. Somaiah   +19 more
semanticscholar   +1 more source

New defining body (Ugras body) in polypoid dedifferentiated liposarcoma of the vallecula. Histomorphological, immunohistochemical and molecular genetic findings

Indian Journal of Pathology and Microbiology, 2020
This is a description of a dedifferentiated liposarcoma seen in a 27-year-old female patient. The tumor originated from the vallecula and contains distinctive bodies.
Serdar Ugras, Markku Miettinen
doaj   +1 more source

Fat‐Containing Soft Tissue Lesions of the Limbs and Body Wall—A Pictorial Essay

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Lipomatous tumours are frequently encountered on imaging. The spectrum of lipomatous tumours ranges from simple lipomas, which can be monitored clinically, to high‐grade liposarcomas, which require timely, multidisciplinary management. The presence of fat within lesions may also be observed in non‐lipomatous tumours, as well as in a variety of
Kai‐Zheong Lim, Cathryn Hui
wiley   +1 more source

Late-onset meningeal metastases in liposarcoma: A case report and review of the literature [PDF]

, 2006
Intracranial metastases from liposarcoma are rare and almost always preceded by the development of systemic tumour spread. We report here a case of liposarcoma with spread to the cranial nervous system 23 years after treatment of the primary tumour.
White, J., Cowie, F., Ferguson, M., Stewart, W.   +3 more
core   +1 more source

Evaluating Fine Needle Aspiration Cytology for Diagnostics of Soft Tissue and Bone Tumours

Cytopathology, EarlyView.
Systematic comparison of needle aspiration cytology and histopathology for 503 tumours in soft tissue and bone showed high concordance (positive predictive value 94%–100%, negative predictive value 83%–89%). In this original study, the authors show that FNAC is a safe and non‐invasive method for diagnosing suspected sarcomas, with the main objective to
Amanda Husu, Sandra Wessman, Karin Wallander, Felix Haglund de Flon   +3 more
wiley   +1 more source

Primary duodenal dedifferentiated liposarcoma: A case report and literature review

World Journal of Clinical Cases, 2022
BACKGROUND Dedifferentiated liposarcoma (DDLPS) is an extremely rare neoplasm that exhibits various morphologies. The tumor is characterized by immunoreactivity to MDM2 and CDK4 and can be confirmed by detecting MDM2 amplification via fluorescence in ...
N. Kim, Ji-Shin Lee, C. Choi, J. Nam, Y. Choi, H. Kim, S. S. Kim   +6 more
semanticscholar   +1 more source