Results 61 to 70 of about 2,061,737 (311)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A General Method for Drawing Area-Proportional Euler Diagrams [PDF]

open access: yes, 2011
Area-proportional Euler diagrams have many applications, for example they are often used for visualizing data in medical and biological domains. There have been a number of recent research efforts to automatically draw Euler diagrams when the areas of ...
Howse, John   +5 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

STRENGTHENING TREATMENT OF DEEP-DRAWING DIES

open access: yesНаука и техника, 2010
The paper investigates a possibility to increase resistance of die tool for deep-drawing while applying surface strengthening with the help of diffusion carbidized coatings.
N. A. Galynskaya   +3 more
doaj  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Increasing the Deep Drawability of Al-1050 Aluminum Sheet using Multi-Point Blank Holder [PDF]

open access: yesMetalurgija, 2006
Aluminum alloys have been widely used in the fields of automobile and aerospace industries. Due to their bad cold-formability in deep drawing, a lot of forming methods have been implemented to increase the drawing height and the limiting drawing rate ...
Gavas, M.
doaj  

Deep Drawing with Macro Structured for an Environmentally Friendly Process

open access: yesJournal of Machine Engineering, 2020
The efficient use of resources are becoming more important due to economic and environmental requirements. In widely used forming processes like deep drawing an avoidance of lubricants – namely dry deep drawing – is a key factor for saving resources.
Alexander BROSIUS, Ali MOUSAVI
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Sheet Forming via Limiting Dome Height (LDH) Test: Influence of the Application of Lubricants, Location and Sheet Thickness on the Micro-Mechanical Properties of X8CrMnNi19-6-3

open access: yesLubricants
This work is concerned with forming, specifically deep drawing, and its influence on the micro-mechanical properties of sheet metal. In practice, there are several applications in which fractions can occur due to weak spots in the deep-drawn sheet metal,
Martin Ovsik   +3 more
doaj   +1 more source

Optimum Design of Microridge Deep Drawing Punch Using Regional Kriging Assisted Fuzzy Multiobjective Evolutionary Algorithm

open access: yesIEEE Access, 2018
This paper introduces an optimized microridge-punch design for deep-drawing processes with improved formability and punch service life. Reducing the thickness of metal sheets results in a marked decrease in the microscale/mesoscale deep drawing rates ...
Suprayitno   +3 more
doaj   +1 more source

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