Results 101 to 110 of about 403,791 (331)

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

Vortex-Induced Vibration of Deep-Sea Mining Pipes: Analysis Using the Slicing Method

Applied Sciences
Deep-sea mining pipes are different from traditional ocean risers articulated at both ends: they are free-suspended, weakly constrained at the bottom, and have an intermediate silo at the end, compared to which relatively little research has been carried
Xiangzhao Wu, Song Sang, Youwei Du, Fugang Liu, Jintao Zhang   +4 more
doaj   +1 more source

Deep-water organic-mineral sediments of the black sea as the object of mining and dewatering [PDF]

, 2014
The results of laboratory investigations of grain-size, physical, mechanical and rheological properties of the deep-sea organic-mineral sediments sampled from the depth of 1,920 – 2,150 m at the polygon “Sapropels” in the Black Sea are given. The results
Francuck, V. P., Shepel, T. V., Shevchenko, O. E.   +2 more
core  

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Numerical simulations and large-scale experimental research into air-lifting system for deep-sea mining

International Journal of Naval Architecture and Ocean Engineering
The deep seabed harbors abundant mineral resources. To achieve the economic viability of deep-sea mining, the efficiency of polymetallic nodule lifting is critical.
JianYu Xiao, Zhuang Kang, Jing Leng, Ming Chen, Jun Liu   +4 more
doaj   +1 more source

Feasibility study on manganese nodules recovery in the Clarion-Clipperton Zone

, 2012
The sea occupies three quarters of the area on the earth and provides various kinds of resources to mankind in the form of minerals, food, medicines and even energy.
Agarwal, Baivau, Hu, Pan, Placidi, Marco, Santo, Harrif, Zhou, Jenny Jin   +4 more
core  

Impact of mining activities in the Upper Silesian Coal Basin on surface water and possibilities of its reduction [PDF]

, 2015
Due to the deposits of quality hard coal, the area of the Upper Silesian Coal Basin (USCB) has been one of the most industrialised regions in Europe for centuries.
Adamczyk, Zdzisław, Grmela, Arnošt, Harat, Andrzej, Rapantová, Naďa   +3 more
core   +2 more sources

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Experimental Study on the Shear Characteristics of Deep-Sea Sediments Based on a Mining Machine Walking Test Platform

Advances in Civil Engineering
The exploitation and utilization of deep-sea mineral resources is an important measure to ensure the safety of resources. The shear characteristics of deep-sea sediments are fundamental parameters for the design of a machine for mining polymetallic ...
Xiaoyan Li, Lang Lei, Shengwei Zhao, Jenisha Singh, Zhou Li   +4 more
doaj   +1 more source

Geologists of Russian origin in Latin America [PDF]

, 2018
Se describe la vida y trayectoria de geólogos que más allá de su nacionalidad (rusa, ucraniana, tártara, alemana, etc.), nacieron en territorios que pertenecieron al Imperio Ruso, la Unión Soviética o la Federación Rusa, y de sus descendientes graduados ...
Alonso, Ricardo, Boltovskoy, Demetrio, Charrier González, Reynaldo, Durand Delga, Michel, Minina, Elena, Riccardi, Alberto Carlos, Tchoumatchenco, Platon, Wiasemsky, Michel   +7 more
core   +1 more source