Results 101 to 110 of about 4,786,586 (289)

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

Advanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen, Bao Chen, Wenhui Zhang, Guifang Sun, Yao Zhao, Jianpeng Zhang, Baofu Xu   +6 more
wiley   +1 more source

Deep Sea Mining: Potential and Controversies in the International Framework

openLa tesi analizza la pratica dell'estrazione mineraria sui fondali marini (Deep sea mining) con un occhio al quadro giuridico internazionale di riferimento, analizzando le criticità giuridiche che questa nuova pratica incontra, coinvolgendo attori ...
PASINI, ALBERTO EMILIO
core  

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications

Advanced Science, EarlyView.
China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu, Zhiyu Tian, Zhengxian Zhang, Xinbei Li   +3 more
wiley   +1 more source

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

Advanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

Vortex-Induced Vibration of Deep-Sea Mining Pipes: Analysis Using the Slicing Method

Applied Sciences
Deep-sea mining pipes are different from traditional ocean risers articulated at both ends: they are free-suspended, weakly constrained at the bottom, and have an intermediate silo at the end, compared to which relatively little research has been carried
Xiangzhao Wu, Song Sang, Youwei Du, Fugang Liu, Jintao Zhang   +4 more
doaj   +1 more source

Alpha radiation from polymetallic nodules and potential health risks from deep-sea mining. [PDF]

Sci Rep, 2023
Volz JB, Geibert W, Köhler D, van der Loeff MMR, Kasten S.   +4 more
europepmc   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source

Deep sea mining poses an unjustifiable environmental risk [PDF]

Deep sea mining could provide a globally significant supply of metals we urgently need to decarbonise our society, yet its environmental impact remains intractable.
K Thompson (8579514), K Littler (16168073), J Scourse (21876788), R Crane (13309533), C Laing (9896417), D Vogt (21920297), K Moore (9720572), C Roberts (7211462)   +7 more
core   +3 more sources

Simulation Experiment of Environmental Impact of Deep-Sea Mining: Response of Phytoplankton Community to Polymetallic Nodules and Sediment Enrichment in Surface Water. [PDF]

Toxics, 2022
Ou R, Cai L, Qiu J, Huang H, Ou D, Li W, Lin F, He X, Wang L, Wu R.   +9 more
europepmc   +1 more source