Results 111 to 120 of about 403,791 (331)
The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis
Advanced Science, EarlyView.SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo +5 more
wiley +1 more source
Journal of Marine Science and EngineeringPrediction of the spatial configuration of the umbilical cable during deep-sea mining in-situ tests is of great significance because dynamic change may cause the umbilical cable to touch the ground or overturn the mining vehicle.
Chaojun Huang +10 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao +14 more
wiley +1 more source
Process pattern of heterogeneous gas hydrate deposits dissociation [PDF]
, 2018 Purpose. Justification of the effective dissociation process parameters of heterogeneous gas hydrate deposits and elaboration of their classification according to the thermal energy consumption. Methodology.
Bоndаrenkо, V.I, Sаi, K.S
core
Advanced Science, EarlyView.Enhancing the utilization efficiency of nutrients recovered from wastewater is achieved through hydrogel modification by biochar. The strategy improves nutrient binding to hydrogels via electron transfer at heterointerfaces, thereby reducing nutrient release rate.
Hao Hu +7 more
wiley +1 more source
New Geothermal Prospect in North-Eastern Morocco [PDF]
, 2010 Geothermal data has been indicating promising potentialities in the north-eastern Morocco. This paperpresents new temperature data, recently recorded in water borehole located in the Berkane and Oujda areas.
Barkaoui, Alae Eddine +7 more
core
Advanced Science, EarlyView.This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao +14 more
wiley +1 more source
Rheological properties of deep-sea shallow sediments in the Western Pacific mining area
Soils and FoundationsStudying the rheological properties of deep-sea shallow sediments can provide basic mechanical characteristics for designing deep-sea mining vehicles driving on the soft seabed, providing anchoring stability of semi-submersible mining platforms, and ...
Hao Liu +8 more
doaj +1 more source
Advanced Science, EarlyView.Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
Research status and analysis of deep-sea metal mining equipment and technologies
Meitan xuebaoMetal mineral resources are critical materials for the world economic development. In a situation of weak supply of terrestrial rare metals, many countries are expanding the direction of resource extraction from a land-based approach to a land-sea ...
Yongping JIN +3 more
doaj +1 more source