Results 51 to 60 of about 1,193,111 (325)

Proteomic Characterization of Proliferation Inhibition of Well-Differentiated Laryngeal Squamous Cell Carcinoma Cells Under Below-Background Radiation in a Deep Underground Environment

Frontiers in Public Health, 2020
Background: There has been a considerable concern about cancer induction in response to radiation exposure. However, only a limited number of studies have focused on the biological effects of below-background radiation (BBR) in deep underground ...
Jifeng Liu, Jifeng Liu, Tengfei Ma, Tengfei Ma, Mingzhong Gao, Yilin Liu, Jun Liu, Shichao Wang, Yike Xie, Qiao Wen, Ling Wang, Juan Cheng, Shixi Liu, Jian Zou, Jian Zou, Jiang Wu, Weimin Li, Heping Xie, Heping Xie, Heping Xie   +19 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Spring phytoplankton of Lake Onego as a trophic resource for deep-water benthos

BIO Web of Conferences
In the past few years the relict deep-water crustacean Monoporeia affinis (Lindström, 1855) has become less abundant in Lake Onego, Europe’s second largest lake. Further studies are needed, therefore, to better understand the formation of spring phytoplankton as food for deep-water benthos.
Kalinkina Nataliia, Slastina Julia
openaire   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Investigation of Mechanical Characterization of Transversely Isotropic Rock Mass Based on Rigid Block Discrete Element Method

Geofluids, 2022
The laminated joints of transversely isotropic rock mass show strong discontinuity, inhomogeneity, anisotropy, and nonlinearity. This paper proposes a novel rigid block discrete element method (RB-DEM) to simulate the transversely isotropic rock mass ...
Kun Qian, Qiang Zhang, Qingxiang Meng, Qian Yin, Chun Zhu, Hangtian Song   +5 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

A comprehensive review of deep learning applications in hydrology and water resources [PDF]

, 2020
Muhammed Sit, Bekir Zahit Demiray, Zhongrun Xiang, Gregory J. Ewing, Yusuf Sermet, İbrahim Demir   +5 more
  +6 more sources

A rotational ellipsoid model for solid Earth tide with high precision

Scientific Reports
Solid Earth tide represents the response of solid Earth to the lunar (solar) gravitational force. The yielding solid Earth due to the force has been thought to be a prolate ellipsoid since the time of Lord Kelvin, yet the ellipsoid’s geometry such as ...
Yongfeng Yang, Yunfei Zhang, Qiang Liu, Xianqing Lv, Pu Huang   +4 more
doaj   +1 more source

Floating wind power in deep-sea area: Life cycle assessment of environmental impacts

Advances in Applied Energy, 2023
Floating offshore wind power, an emerging technology in the offshore wind industry, has attracted increasing attention for its potential to cooperate with other renewable energies to decarbonize energy systems.
Weiyu Yuan, Jing-Chun Feng, Si Zhang, Liwei Sun, Yanpeng Cai, Zhifeng Yang, Songwei Sheng   +6 more
doaj   +1 more source

Report of Investigations No. 141 Hydrogeology of the Edwards Aquifer, Austin Area, Central Texas [PDF]

, 1984
UT ...
Kreiter, Charles W., Senger, Rainer K.
core   +1 more source