Results 51 to 60 of about 174,348 (267)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Landslide Susceptibility Mapping Using an Image–Tabular Joint Deep Learning Framework: A Case Study of the Tacheng Region, Xinjiang, China

Remote Sensing
Accurate landslide susceptibility mapping (LSM) is important for hazard prevention and land use planning in mountainous regions. Existing machine learning and deep learning methods mainly use raster-based conditioning factors. They often ignore landslide-
Qianjie Deng, Dingfan Xing, Xiong Wu, Lirui Song, Zhuoer Teng, Rui Wang, Shichen Gao, Zhiwu Zhang, Kun-Feng Qiu   +8 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Sexual maturity of the deep-sea royal crab Chaceon ramosae Manning, Tavares & Albuquerque, 1989 (Brachyura: Geryonidae) in southern Brazil Madurez sexual del cangrejo real Chaceon ramosae Manning, Tavares & Albuquerque, 1989 (Brachyura: Geryonidae) en el sur de Brasil

Latin American Journal of Aquatic Research, 2009
The royal crab Chaceon ramosae is one of the three species of deep-sea crabs currently exploited in Brazil. The royal crab fishery started in 2001 with foreign vessels that were extensively monitored by observers and tracked by satellite.
Paulo Ricardo Pezzuto, Rodrigo Sant'Ana
doaj  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Mechanical behaviors and rupture processes of a typical granitic stratum

Journal of Rock Mechanics and Geotechnical Engineering
Granitic veins (GVs) have a significant influence on the mechanical responses of tunnels excavated in granitic strata. Distinguishing the mechanical properties of host granites (HGs), GVs and vein-granite interfaces (VGIs) is critical.
Xiaofang Nie, Dong Wang, Song Yuan, Liangpu Li, Zhilong Zhang, Zidong Fan, Qin Zhou, Meng Wang, Li Ren   +8 more
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

HERMES: Promoting Ecosystem-Based Management and the Sustainable Use and Governance of Deep-Water Resources

Oceanography, 2009
HERMES is much more than a scientific research project. The overall goal of the project is to improve the scientific basis for the sustainable use of Europe's offshore resources with due regard for the need to conserve vulnerable deep-sea ecosystems.
Grehan, Anthony J., van den Hove, Sybille, Armstrong, Claire W., Long, Ronan, van Rensburg, Thomas, Gunn, Vikki, Mikkelsen, Eirik, De Mol, Ben, Hain, Stefan   +8 more
openaire   +2 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Water Resources Identification in Barren Lands Using Deep Learning Techniques [PDF]

EPJ Web of Conferences
This paper introduces a hybrid deep learning architecture to precisely detect surface water resources in deserted and dry areas in Central India with Sentinel-2 RGB images.
Balasubramanian Prabha, Ajithbabu Abijith   +1 more
doaj   +1 more source