Results 71 to 80 of about 135,935 (307)

In Parkinson’s disease dopaminergic medication and deep brain stimulation of the subthalamic nucleus increase motor, but not reflection and cognitive impulsivity

open access: yesFrontiers in Neuroscience
BackgroundParkinson’s disease is associated with increased impulsivity, which can be divided into several domains: motor (consisting of proactive and reactive subdomains), reflection, and cognitive impulsivity.
Martijn Hendriks   +10 more
doaj   +1 more source

Computational analysis of transcranial magnetic stimulation in the presence of deep brain stimulation probes

open access: yesAIP Advances, 2017
Transcranial Magnetic Stimulation is an emerging non-invasive treatment for depression, Parkinson’s disease, and a variety of other neurological disorders. Many Parkinson’s patients receive the treatment known as Deep Brain Stimulation, but often require
F. Syeda   +3 more
doaj   +1 more source

Deep brain stimulation of different pedunculopontine targets in a novel rodent model of parkinsonism

open access: yes, 2015
The pedunculopontine tegmental nucleus (PPTg) has been proposed as a target for deep brain stimulation (DBS) in parkinsonian patients, particularly for symptoms such as gait and postural difficulties refractory to dopaminergic treatments.
Winn, Philip   +3 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Vestibular Evoked Myogenic Potentials (VEMPs) in Parkinson’s Disease Patients with Monopolar Deep Brain Stimulation

open access: yesSignals
Whilst balance disturbances are common in people with advanced Parkinson’s disease, it has not previously been possible to record vestibular evoked myogenic potentials (VEMPs), and thus otolithic function, during monopolar deep brain stimulation (DBS ...
Kim E. Hawkins   +5 more
doaj   +1 more source

IncobotulinumtoxinA and Deep Brain Stimulation [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2019
ABSTRACT:Guidelines recommend Botulinum toxin-A (BoNT-A) after deep brain stimulation (DBS), although the effectiveness of their combined use is uncertain. A chart review of Parkinson’s disease (17) and dystonia (7) patients undergoing 302 injections with IncobotulinumtoxinA before or after DBS was performed.
Derrick, Soh, Alfonso, Fasano
openaire   +2 more sources

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Early Experiences with Robotic-assisted Implantation of Deep Brain Stimulation Electrodes in Awake or Asleep Patients in Japan

open access: yesNeurologia Medico-Chirurgica
This study evaluated 14 patients who underwent robot-assisted deep brain stimulation electrode implantation and described our early experiences and workflows in both awake and asleep states.
Masafumi FUKUDA   +4 more
doaj   +1 more source

Parasomnia overlap disorder, Parkinson's disease and subthalamic deep brain stimulation: three case reports. [PDF]

open access: yes, 2017
BACKGROUND Parasomnia overlap disorder (POD) is a distinct parasomnia and characterized by concomitant manifestation of rapid-eye-movement (REM)- and non-REM (NREM)-parasomnias.
Bassetti, Claudio   +3 more
core   +1 more source

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