Results 51 to 60 of about 4,865,431 (261)

Deep brain stimulation and tics

, 2014
When patients with Tourettes syndrome (TS) are refractory to behavioral, pharmacological and invasive nonsurgical treatment (botulinum toxin injection), a viable emerging option is deep brain stimulation (DBS)
Priori A.
core   +2 more sources

Deep brain stimulation beneficial for treatment-resistant depression: A systematic review and meta-analysis of clinical trials and long-term follow-up studies

Deep Brain Stimulation
Background: Many conventional treatments for MDD (major depressive disorder) fail to prove clinical efficacy, which highlight the urgent need for novel treatments.
Ali Sepas, Hussein Alkafaji, Vedat Atici, Carsten R. Bjarkam, Torben Moos   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Management of stimulation-induced dyskinesia after subthalamic deep brain stimulation in a 19-year-old patient with obsessive-compulsive disorder: A case report

Deep Brain Stimulation
Background: Deep brain stimulation (DBS) is a promising treatment option for obsessive compulsive disorders (OCD). Here, we report the case of a young 19-year-old patient, diagnosed with severe OCD since the age of 12 and has exhibited contamination ...
Abdelhamid Benazzouz, Sarah Belarabi, Sarah Mliyahe, Rachid Aalouane, Rabia Bouali-Benazzouz, Mohammed Chaoui El Faiz, Mohammed Faouzi Belahsen   +6 more
doaj   +1 more source

Effect of sevoflurane on neuronal activity during deep brain stimulation surgery for epilepsy: A case report

Interdisciplinary Neurosurgery, 2018
Deep brain stimulation of the anterior nucleus of the thalamus is an effective treatment for patients with refractory epilepsy who do not respond sufficiently to medical therapy.
Michaël J. Bos, MD, Linda Ackermans, MD, PhD, Frédéric L.W.V.J. Schaper, MD, Rob P.W. Rouhl, MD, PhD, Vivianne H.J.M. van Kranen-Mastenbroek, MD, PhD, Wolfgang F. Buhre, MD, PhD, Marcus L.F. Janssen, MD, PhD   +6 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Patient perspectives on closed-loop deep brain stimulation: An exploratory study

Deep Brain Stimulation
Deep Brain Stimulation (DBS) technologies have expanded to include closed-loop DBS (CL-DBS), which adjusts stimulation parameters in real-time. Potential advantages in the treatment of movement disorders, such as Parkinson Disease (PD), include improved ...
Dara I. Nitu, Lara Strüder, Elise M.C. Claux, Gonzalo Lozano Laporta, Tem H.J. Hermans, Greta L. Jendrock, David E.J. Linden, Marcus L.F. Janssen, Stefanie C. Linden   +8 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Deep Brain Stimulation and Drug-Resistant Epilepsy: A Review of the Literature

Frontiers in Neurology, 2019
Introduction: Deep brain stimulation is a safe and effective neurointerventional technique for the treatment of movement disorders. Electrical stimulation of subcortical structures may exert a control on seizure generators initiating epileptic activities.
Nasser Zangiabadi, Nasser Zangiabadi, Lady Diana Ladino, Farzad Sina, Juan Pablo Orozco-Hernández, Alexandra Carter, José Francisco Téllez-Zenteno   +6 more
doaj   +1 more source

Surgical management of adverse events associated with deep brain stimulation: A single-center experience

SAGE Open Medicine, 2020
Objectives: Deep brain stimulation is widely used to treat movement disorders and selected neuropsychiatric disorders. Despite the fact, the surgical methods vary among centers.
Masani Nonaka, Takashi Morishita, Kazumichi Yamada, Shinsuke Fujioka, Masa-aki Higuchi, Yoshio Tsuboi, Hiroshi Abe, Tooru Inoue   +7 more
doaj   +1 more source