Results 51 to 60 of about 318,376 (281)

Desynchronizing effect of high-frequency stimulation in a generic cortical network model

, 2012
Transcranial Electrical Stimulation (TCES) and Deep Brain Stimulation (DBS) are two different applications of electrical current to the brain used in different areas of medicine. Both have a similar frequency dependence of their efficiency, with the most
A Antal, A Antal, A Benabid, A Compte, A Gupta, A Limoge, A Limoge, A Sances Jr, AS Pikovsky, B Nuttin, C Börgers, CC McIntyre, E Schöll, EM Izhikevich, EM Izhikevich, EM Izhikevich, EM Izhikevich, F Velasco, H Markram, J Lian, J Yianni, JA Acebrón, JA Obesó, JD Geyer, Jens Christian Claussen, JL Houeto, KJ Ressler, L Gang, L Garcia, M Steriade, Markus Schütt, P Coubes, R Kumar, R Wang, SC Bellinger, TR Anderson, V Visser-Vandewalle, X Zhang, Y Liu, Y Su   +39 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Rehabilitation based on brain-computer interface for aphasic patients: A systematic review

Deep Brain Stimulation
Aphasia is the disturbance of language production and/or comprehension. From 25–40 % of patients with stroke manifest aphasia. Although many rehabilitation techniques are known, a large percentage of these patients do not recover language function.
Massimiliano Domenico Rizzaro, Luigi Gianmaria Remore, Valeria Lo Faso, Giorgio Fiore, Luigi Schisano, Elena Pirola, Antonella Ampollini, Giulio Andrea Bertani, Stefania Elena Navone, Giovanni Marfia, Marco Locatelli   +10 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Deep Brain Stimulation and Drug-Resistant Epilepsy: A Review of the Literature

Frontiers in Neurology, 2019
Introduction: Deep brain stimulation is a safe and effective neurointerventional technique for the treatment of movement disorders. Electrical stimulation of subcortical structures may exert a control on seizure generators initiating epileptic activities.
Nasser Zangiabadi, Nasser Zangiabadi, Lady Diana Ladino, Farzad Sina, Juan Pablo Orozco-Hernández, Alexandra Carter, José Francisco Téllez-Zenteno   +6 more
doaj   +1 more source

2008 Progress Report on Brain Research [PDF]

, 2008
Highlights new research on various disorders, nervous system injuries, neuroethics, neuroimmunology, pain, sense and body function, stem cells and neurogenesis, and thought and memory.
Eve Marder, Mahlon R. DeLong, Michael S. Gazzaniga, Thomas Wichmann   +3 more
core  

Impact of sub-thalamic nucleus deep brain stimulation on dual tasking gait in Parkinson’s disease [PDF]

, 2013
Background: The beneficial effects of bilateral sub-thalamic nucleus deep brain stimulation on motor function and gait in advanced Parkinson’s disease are established.
Hausdorff, Jeffrey M., Israel, Zvi, Seri-Fainshtat, Eliraz, Weiss, Aner   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Deep brain stimulation: An overview of history, methods, and future developments

Brain and Neuroscience Advances, 2018
Deep brain stimulation has already revolutionised the clinical management of treatment-resistant movement disorders and offers novel treatment options for an increasing range of neurological and psychiatric illnesses.
Laurie Pycroft, John Stein, Tipu Aziz
doaj   +1 more source

Multi-Disease Deep Brain Stimulation

IEEE Access, 2020
Current closed-loop deep brain stimulation (DBS) devices can generally tackle one disorder. This paper presents the design and evaluation of a multi-disease closed-loop DBS device that can sense multiple brain biomarkers, detect a disorder, and ...
Mahboubeh Parastarfeizabadi, Roy V. Sillitoe, Abbas Z. Kouzani   +2 more
doaj   +1 more source