Results 31 to 40 of about 4,865,431 (261)

Cross-hemispheric effects of subthalamic nucleus deep-brain stimulation in Parkinson’s disease

open access: yesDeep Brain Stimulation
Subthalamic nucleus (STN) deep brain stimulation (DBS) is an effective treatment for Parkinson’s disease in patients who have developed complications of levodopa therapy.
Bruce Chase   +4 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko   +5 more
wiley   +1 more source

Adaptive deep brain stimulation (aDBS)

open access: yes, 2021
Deep brain stimulation is an established technique for the treatment of movement disorders related to neurodegenerative diseases such as Parkinson's disease (PD) and essential tremor (ET).
Dini M.   +5 more
core   +1 more source

Targeting pain with deep brain stimulation: Insights into the thalamus and associated structures

open access: yesDeep Brain Stimulation
Chronic pain is a major public health issue, and despite advances in understanding its pathophysiology, current treatments remain insufficient, significantly affecting patients' quality of life.
Rabia Bouali-Benazzouz   +2 more
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba   +29 more
wiley   +1 more source

Pulse-width modulated temporal interference (PWM-TI) brain stimulation

open access: yes, 2023
BACKGROUND: Electrical stimulation involving temporal interference of two different kHz frequency sinusoidal electric fields (temporal interference (TI)) enables non-invasive deep brain stimulation by creating an electric field that is amplitude ...
Dzialecka, Patrycja   +4 more
core   +1 more source

Deep brain stimulation as a treatment for chronic pain: A narrative and historical review

open access: yesDeep Brain Stimulation
Chronic pain is one of the most common causes for patients to seek medical aid, but the currently available therapeutic interventions fail to meet the needs of many patients.
Zack Reynolds   +4 more
doaj   +1 more source

Deep brain stimulation of the nucleus accumbens core but not shell reduces motivational components of heroin taking and seeking in rats

open access: yesBrain and Neuroscience Advances, 2017
Background: Deep brain stimulation is explored as a new intervention for treatment-resistant substance use dependence. A candidate brain region is the nucleus accumbens, due to its involvement in reward and motivation. This study aimed to explore effects
Maria C. Schippers   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Deep brain stimulation for management of treatment-refractory schizophrenia: A translational review for clinical integration

open access: yesDeep Brain Stimulation
Background and hypothesis: With a typical clinical onset in late adolescence and early adulthood, schizophrenia is a severe illness and one of the top ten global causes of disability.
Cristina D. Ghinda   +5 more
doaj   +1 more source

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