Results 31 to 40 of about 121,878 (259)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Deep brain stimulation for dystonia
Expert Review of Medical Devices, 2004 Dystonia is a movement disorder characterized by involuntary muscular contractions that generate twisting and repetitive movements and/or abnormal postures. It can affect a few muscle groups (focal dystonia) or spread to most muscles in the body (generalized dystonia).
Michele, Tagliati +3 more
openaire +5 more sources
Deep Brain StimulationBackground and hypothesis: With a typical clinical onset in late adolescence and early adulthood, schizophrenia is a severe illness and one of the top ten global causes of disability.
Cristina D. Ghinda +5 more
doaj +1 more source
Interdisciplinary Neurosurgery, 2018 Deep brain stimulation of the anterior nucleus of the thalamus is an effective treatment for patients with refractory epilepsy who do not respond sufficiently to medical therapy.
Michaël J. Bos, MD +6 more
doaj +1 more source
Deep brain stimulation for dystonia [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 2012 The few controlled studies that have been carried out have shown that bilateral internal globus pallidum stimulation is a safe and long-term effective treatment for hyperkinetic disorders. However, most recent published data on deep brain stimulation (DBS) for dystonia, applied to different targets and patients, are still mainly from uncontrolled case ...
Marie, Vidailhet +3 more
openaire +3 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Contribution of animal models to DBS research in movement and psychiatric disorders: A review
Deep Brain StimulationDeep brain stimulation (DBS) has evolved through a dynamic interplay between clinical and pre-clinical research. Initially inspired by invasive clinical practices such as ablations, resections, and other lesion-based interventions, minimally-invasive ...
David Dominguez-Paredes +3 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Rehabilitation based on brain-computer interface for aphasic patients: A systematic review
Deep Brain StimulationAphasia is the disturbance of language production and/or comprehension. From 25–40 % of patients with stroke manifest aphasia. Although many rehabilitation techniques are known, a large percentage of these patients do not recover language function.
Massimiliano Domenico Rizzaro +10 more
doaj +1 more source
SAGE Open Medicine, 2020 Objectives: Deep brain stimulation is widely used to treat movement disorders and selected neuropsychiatric disorders. Despite the fact, the surgical methods vary among centers.
Masani Nonaka +7 more
doaj +1 more source