Results 11 to 20 of about 318,376 (281)

Directional Deep Brain Stimulation [PDF]

Neurotherapeutics, 2019
Over the last years, deep brain stimulation has seen many technological innovations. New electrode designs allowing to direct the current flow not only in the vertical but also in the horizontal plane are the most recent. We summarize the concept of "directional deep brain stimulation" with its opportunities and challenges and the available study data ...
Frank Steigerwald, Cordula Matthies, Jens Volkmann   +2 more
openaire   +2 more sources

Neural plasticity in human brain connectivity: the effects of long term deep brain stimulation of the subthalamic nucleus in Parkinson's disease. [PDF]

PLoS ONE, 2014
Positive clinical outcomes are now well established for deep brain stimulation, but little is known about the effects of long-term deep brain stimulation on brain structural and functional connectivity.
Tim J van Hartevelt, Joana Cabral, Gustavo Deco, Arne Møller, Alexander L Green, Tipu Z Aziz, Morten L Kringelbach   +6 more
doaj   +1 more source

Discovering Themes in Deep Brain Stimulation Research Using Explainable Artificial Intelligence

Biomedicines, 2023
Deep brain stimulation is a treatment that controls symptoms by changing brain activity. The complexity of how to best treat brain dysfunction with deep brain stimulation has spawned research into artificial intelligence approaches. Machine learning is a
Ben Allen
doaj   +1 more source

Optogenetics and deep brain stimulation neurotechnologies [PDF]

, 2015
Brain neural network is composed of densely packed, intricately wired neurons whose activity patterns ultimately give rise to every behavior, thought, or emotion that we experience. Over the past decade, a novel neurotechnique, optogenetics that combines
A Berndt, A Berndt, A Priori, AA Kuhn, AA Kuhn, AS Chuong, B Sauer, B Wingeier, BY Chow, BY Chow, C Bamann, D Luo, D Oesterhelt, D Oesterhelt, D Williams, ES Boyden, EY Uc, F Zhang, F Zhang, G Foffani, G Miesenbock, G Nagel, J Cavanaugh, J Mobley, J Volkmann, J Wells, J Wietek, JG Bernstein, JG Bernstein, JG Bernstein, JL Spudich, JL Spudich, JO Dostrovsky, JZ Tsien, L Bekar, L Madisen, LA Gunaydin, M Weinberger, M Weinberger, MC Rodriguez-Oroz, MJ Lehmkuhle, ML Welter, MM Doroudchi, O Yizhar, P Brown, P Silberstein, R Levy, R Levy, R Levy, R Waehler, S Zhao, TW Chen, VC Anderson, X Han, X Han, X Han, X Han, X Han, X Liu   +58 more
core   +2 more sources

Deep Brain Stimulation in Schizophrenia [PDF]

Activitas Nervosa Superior, 2014
Abstract Deep brain stimulation (DBS) has successfully advanced treatment options of putative therapy-resistant neuropsychiatric diseases. Building on this strong foundation more and more mental disorders in the stadium of therapy-resistance are considered as possible indications for DBS.
Kuhn, J., Bodatsch, M., Sturm, V., Lenartz, D., Klosterkötter, J., Uhlhaas, P.J., Winter, C., Gruendler, T.O.J.   +7 more
openaire   +3 more sources

Does Impaired Plantar Cutaneous Vibration Perception Contribute to Axial Motor Symptoms in Parkinson’s Disease? Effects of Medication and Subthalamic Nucleus Deep Brain Stimulation

Brain Sciences, 2023
Objective: To investigate whether impaired plantar cutaneous vibration perception contributes to axial motor symptoms in Parkinson’s disease (PD) and whether anti-parkinsonian medication and subthalamic nucleus deep brain stimulation (STN-DBS) show ...
Tobias Heß, Peter Themann, Christian Oehlwein, Thomas L. Milani   +3 more
doaj   +1 more source

Neurosurgery for Psychopaths? An Ethical Analysis [PDF]

, 2016
Recent developments in neuroscience have inspired proposals to perform deep brain stimulation on psychopathic detainees. We contend that these proposals cannot meet important ethical requirements that hold for both medical research and therapy.
Hübner, Dietmar, White, Lucie
core   +1 more source

Deep brain and cortical stimulation for epilepsy [PDF]

, 2014
Background : Despite optimal medical treatment, including epilepsy surgery, many epilepsy patients have uncontrolled seizures. In the last decades, interest has grown in invasive intracranial neurostimulation as a treatment for these patients ...
Anderson, Andrade, Becker, Beyenburg, Boon, Borghs, Boëx, Buren, Chabardes, Chkhenkeli, Cramer, Cramer, Curtin, Deeks, Devinsky, Elbourne, Elisevich, Engel, Fisher, Fisher, Fisher, Forsgren, Franzini, Handforth, Hodaie, Jehi, Katariwala, Kellinghaus, Khan, Kwan, Kwan, Kwan, Lim, Lim, McLachlan, Morrell, Neligan, Parrent, Privitera, Raftopoulos, Raftopoulos, Rijckevorsel, Rijckevorsel, Salanova, Schulze-Bonhage, Schulze-Bonhage, Selwa, Stedman, Tellez-Zenteno, Tellez-Zenteno, Tisi, Tomson, Valentin, Velasco, Velasco, Velasco, Velasco, Velasco, Velasco, Vonck, Wiebe, Wille, Wright, Zou   +63 more
core   +1 more source

Sex Disparities in the Self-Evaluation of Subthalamic Deep Brain Stimulation Effects on Mood and Personality in Parkinson's Disease Patients

Frontiers in Neurology, 2020
Changes in personality are one of the main concerns Parkinson's disease (PD) patients raise when facing the decision to undergo neurosurgery for deep brain stimulation (DBS) of the subthalamic nucleus (STN).
Amelie D. Dietrich, Johannes A. Koeppen, Carsten Buhmann, Monika Pötter-Nerger, Hans O. Pinnschmidt, Christian Oehlwein, Marita Oehlwein, Katrin Mittmann, Christian Gerloff, Andreas K. Engel, Manfred Westphal, Miriam Schaper, Wolfgang Hamel, Christian K. E. Moll, Alessandro Gulberti, Alessandro Gulberti   +15 more
doaj   +1 more source

Neurosurgeons perspective on the shift towards earlier use of deep brain stimulation for Parkinson disease

Interdisciplinary Neurosurgery, 2021
Background: The US Food and Drug Administration approved in 2015 the use of deep brain stimulation for Parkinson disease after “four years duration and with recent onset of motor complications”.
Paola Testini, Harini Sarva, Jason Schwalb, Samantha Barkan, Laura Y. Cabrera   +4 more
doaj   +1 more source