Deep brain stimulation Abstract. Deep brain stimulation, a neurosurgical therapy, consists of implanting electrodes in certain brain regions via which electrical impulses are applied by means of a neurostimulator (brain pacemaker).
Flavio Fröhlich
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Understanding Autonomic Control via Human Deep Brain Stimulation [PDF]
The Central Autonomic Network (CAN) consists of higher cortical areas, basal ganglia, and brainstem areas that are important in the control of the autonomic nervous system (ANS).
Green, A.
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Trends in Clinical Deep Brain Stimulation
This book covers the current trends in clinical deep brain stimulation (DBS) research. This collection of papers from experts in the field provides state of the art knowledge and future perspectives in clinical DBS research. A range of topics involved in
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Phase dependent modulation of tremor amplitude in essential tremor through thalamic stimulation [PDF]
High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. Here we explore how the efficacy, efficiency and selectivity of thalamic deep brain stimulation might be improved in this condition.
Green, Alexander L +23 more
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Evaluation of Thiel cadaveric model for MRI-guided stereotactic procedures in neurosurgery [PDF]
Magnetic resonance imaging (MRI)-guided deep brain stimulation (DBS) and high frequency focused ultrasound (FUS) is an emerging modality to treat several neurological disorders of the brain.
Eljamel, Sam +4 more
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Deep Brain Stimulation for Disabling “Outflow” Tremors
“Outflow” tremors, sometimes referred to in the literature by a variety of terms (outflow, rubral, midbrain, Holmes), are frequently associated with significant disability and are notoriously unresponsive or only partially responsive to medical treatment.
Shpiner, Danielle S +8 more
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Early Globus Pallidus Internus Stimulation in Pediatric Patients With Generalized Primary Dystonia: Long-Term Efficacy and Safety [PDF]
Primary generalized dystonia presents mainly at a young age and commonly is severely disabling. The authors report the long-term follow-up (mean, 73 months; range, 50-101 months) of 5 pediatric patients (mean age at surgery 13 years; range, 8-16 years ...
Feddersen, Berend +4 more
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An Electromagnetic Study of the Impact of Brain Anatomy on Deep Brain Stimulation [PDF]
An electromagnetic simulation was performed to assess the volume of tissue activated on deep brain stimulation for two patients randomly selected. The finite element method is used to calculate the electric field distribution that predicts the volume of ...
Bajo, R +19 more
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Deep brain stimulation of different pedunculopontine targets in a novel rodent model of parkinsonism [PDF]
The pedunculopontine tegmental nucleus (PPTg) has been proposed as a target for deep brain stimulation (DBS) in parkinsonian patients, particularly for symptoms such as gait and postural difficulties refractory to dopaminergic treatments.
Winn, Philip +3 more
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A brain network for deep brain stimulation induced cognitive decline in Parkinson’s disease [PDF]
Reich et al. show that DBS-induced cognitive decline is associated with connectivity between the stimulation site and a specific brain network implicated in lesion-induced memory impairment. Transforming this network into a heat map can help identify DBS
Hsu Joey +32 more
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