Results 21 to 30 of about 120,651 (160)

Deep Brain Stimulation for Depression

Neurotherapeutics, 2022
Deep brain stimulation has been extensively studied as a therapeutic option for treatment-resistant depression (TRD). DBS across different targets is associated with on average 60% response rates in previously refractory chronically depressed patients. However, response rates vary greatly between patients and between studies and often require extensive
Martijn Figee, Patricio Riva-Posse, Ki Sueng Choi, Lucia Bederson, Helen S. Mayberg, Brian H. Kopell   +5 more
openaire   +2 more sources

Adaptive Deep Brain Stimulation for sleep stage targeting in Parkinson’s disease

Brain Stimulation, 2023
Background: Sleep dysfunction is disabling in people with Parkinson’s disease and is linked to worse motor and non-motor outcomes. Sleep-specific adaptive Deep Brain Stimulation has the potential to target pathophysiologies of sleep.
Clay Smyth, Md Fahim Anjum, Shravanan Ravi, Timothy Denison, Philip Starr, Simon Little   +5 more
doaj   +1 more source

Functional imaging of deep brain stimulation in dystonia: a review

Dystonia, 2023
Much remains to be learned about the mechanism of benefit of deep brain stimulation in movement disorders in general and dystonia specifically. A full accounting of the pathophysiology of dystonia additionally remains unclear.
Ian O. Bledsoe, Melanie A. Morrison
doaj   +1 more source

Directional Deep Brain Stimulation [PDF]

Neurotherapeutics, 2019
Over the last years, deep brain stimulation has seen many technological innovations. New electrode designs allowing to direct the current flow not only in the vertical but also in the horizontal plane are the most recent. We summarize the concept of "directional deep brain stimulation" with its opportunities and challenges and the available study data ...
Frank Steigerwald, Cordula Matthies, Jens Volkmann   +2 more
openaire   +2 more sources

Deep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome

Frontiers in Psychiatry
IntroductionIrritable bowel syndrome (IBS) is a common condition characterized by abdominal pain and altered bowel habits, affecting around 11% of individuals globally.
Mohamed A. Abdelnaim, Mohamed A. Abdelnaim, Tobias Hebel, Verena Lang-Hambauer, Verena Lang-Hambauer, Juergen Schlaier, Juergen Schlaier, Berthold Langguth, Berthold Langguth, Andreas Reissmann   +9 more
doaj   +1 more source

Deep brain stimulation of the nucleus accumbens core but not shell reduces motivational components of heroin taking and seeking in rats

Brain and Neuroscience Advances, 2017
Background: Deep brain stimulation is explored as a new intervention for treatment-resistant substance use dependence. A candidate brain region is the nucleus accumbens, due to its involvement in reward and motivation. This study aimed to explore effects
Maria C. Schippers, Mathijs Gaastra, Tanja Mesman, Dustin Schetters, Yvar van Mourik, Damiaan Denys, Tommy Pattij, Taco J. De Vries   +7 more
doaj   +1 more source

The quest for a target and the beginning of the DBS-story

Deep Brain Stimulation
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has revolutionized the treatment of Parkinson’s disease. It is considered as a treatment of choice, after Levodopa, for patients suffering from advanced stages of the disease.
Abdelhamid Benazzouz
doaj   +1 more source

The Oscillatory Profile Induced by the Anxiogenic Drug FG-7142 in the Amygdala–Hippocampal Network Is Reversed by Infralimbic Deep Brain Stimulation: Relevance for Mood Disorders

Biomedicines, 2021
Anxiety and depression exhibit high comorbidity and share the alteration of the amygdala–hippocampal–prefrontal network, playing different roles in the ventral and dorsal hippocampi.
Hanna Vila-Merkle, Alicia González-Martínez, Rut Campos-Jiménez, Joana Martínez-Ricós, Vicent Teruel-Martí, Arantxa Blasco-Serra, Ana Lloret, Pau Celada, Ana Cervera-Ferri   +8 more
doaj   +1 more source

Neurophysiology in deep brain stimulation: Bridging clinical practice and systems neuroscience

Deep Brain Stimulation
As understanding of neurophysiology has progressed from individual neurons to large-scale brain networks, deep brain stimulation (DBS) has been established as a major intervention for neurological and psychiatric diseases. Here we review (1) the clinical
Julie Lewentz, Mark J. Roberts, Marcus L.F. Janssen   +2 more
doaj   +1 more source

Targeting pain with deep brain stimulation: Insights into the thalamus and associated structures

Deep Brain Stimulation
Chronic pain is a major public health issue, and despite advances in understanding its pathophysiology, current treatments remain insufficient, significantly affecting patients' quality of life.
Rabia Bouali-Benazzouz, Pascal Fossat, Abdelhamid Benazzouz   +2 more
doaj   +1 more source