Results 131 to 140 of about 1,059,912 (346)

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

A material model for aluminium sheet forming at elevated temperatures [PDF]

open access: yes, 2001
In order to accurately simulate the deep drawing or stretching of aluminum sheet at elevated\ud temperatures, a model is required that incorporates the temperature and strain-rate dependency of the material.\ud In this paper two models are compared: a ...
Bolt, P.J.   +2 more
core   +2 more sources

Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow   +4 more
wiley   +1 more source

From Polylithic to Monolithic: The Design of a Lightweight, Stiffened, Non-Rotational, Deep-Drawn Automotive Product

open access: yesDesigns
The transition from polylithic (composed of many parts) to monolithic (one part) design in automotive components presents an opportunity for a reduction in part count, weight, processing routes, and production time without compromising performance.
Gibson P. Chirinda   +3 more
doaj   +1 more source

Analisis Tegangan pada Pembentukan Komponengrommet Gasket Exhaust Sepeda Motor melalui Deep Drawing [PDF]

open access: yes, 2007
Dalam proses pembentukan komponen grommet gasket exahust sepeda motor melalui deep drawing sangat dimungkinkan terjadi kegagalan proses yang akan berdampak terhadap penurunan produktifitas pada proses produksi.
Rahardjo, S. (Soegiatmo)   +1 more
core   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Home - About - Disclaimer - Privacy