Results 141 to 150 of about 116,064 (306)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos   +9 more
wiley   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

TALAT Lecture 3704: Deep Drawing

open access: yes, 2010
This lecture gives definition and explanation of terms; it teaches the most important fundamental laws governing deep drawing; it explains special considerations for deep drawing of aluminium sheet metal.
S Wagner, Institut für Umformtechnik, Universität Stuttgart   +2 more
core  

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro   +6 more
wiley   +1 more source

A short lead time methodology for design, compensation and manufacturing of deep drawing tools for Inconel 718 [Elektronisk resurs]

open access: yes, 2008
This paper presents a systematic methodology for the design and manufacturing of deep drawing tools generating high quality components at an extremely short lead time. Prototype tools for five different super alloy Inconel 718 sheet metal components were
Odenberger, Eva-Lis   +4 more
core  

Additive Manufacturing of a deep drawing tool by direct laser deposition [PDF]

open access: yes, 2015
An additive manufacturing process generating a deep drawing tool by direct laser deposition is described in this paper. Aluminum bronze with ten percent of aluminum content was used as a tool material.
Freiße, Hannes
core  

Lubricant-free deep drawing using CO

open access: yes, 2019
Most metal forming processes use lubricants based on mineral oils as an intermediate medium to reduce friction and wear. To avoid the well-known drawbacks of oil lubrication, a novel and environment friendly lubrication system for deep-drawing processes ...
Daniel J. Foerster   +8 more
core   +1 more source

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