Results 61 to 70 of about 1,059,912 (346)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Ear height control by die radius shape in cylindrical deep drawing [PDF]

MATEC Web of Conferences
This study presents the relationship between die radius shape and anisotropy that suppresses ear height in cylindrical deep drawing. In deep drawing, the cup is formed with irregularities on the edge, called “earing”, due to the anisotropy of sheet ...
Muraoka Tsuyoshi, Okude Yusuke, Nakamura Isao, Katagiri Takashi   +3 more
doaj   +1 more source

Allegory as Experiential Communication: Metaphorical Mapping between Bunyan’s Emotions and The Pilgrim’s Progress [PDF]

, 2018
John Bunyan’s The Pilgrim’s Progress (1678) is a classic example of allegory. While literary critics tend to minimize allegory’s value as a mode, The Pilgrim’s Progress demonstrates a proclivity for genre-transcending techniques that encourage looking at
Sitterding, Philip
core   +1 more source

Experimental and numerical study of micro deep drawing [PDF]

, 2015
© 2015 Owned by the authors, published by EDP Sciences. Micro forming is a key technology for an industrial miniaturisation trend, and micro deep drawing (MDD) is a typical micro forming method.
Jiang, Z, Luo, L, Manabe, KI, Sato, H, Wei, D   +4 more
core   +2 more sources

Earing in Deep‐Drawing Steels [PDF]

Texture, Stress, and Microstructure, 1974
The variations of the fourth‐order coefficients of the crystallite orientation distribution function, with rolling reduction have been determined after cold‐rolling and annealing for a deep‐drawing quality rimming steel and an aluminium‐killed steel.
Davies, GJ, Goodwill, DJ, Kallend, JS
openaire   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

STRENGTHENING TREATMENT OF DEEP-DRAWING DIES

Наука и техника, 2010
The paper investigates a possibility to increase resistance of die tool for deep-drawing while applying surface strengthening with the help of diffusion carbidized coatings.
N. A. Galynskaya, N. G. Koukhareva, S. N. Petrovich, G. V. Stassevich   +3 more
doaj  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

FEM SIMULATION OF DEEP DRAWING PROCESS OF ALUMINIUM ALLOYS [PDF]

Applied Computer Science, 2015
This paper presents results of research with FEM simulation of sheet metal forming process. The two types of aluminium alloys from 5XXX and 6XXX series, which are used in automotive industry, were compared.
Jan SLOTA, Ivan GAJDOS, Tomasz JACHOWICZ, Marek SISER, Volodymyr KRASINSKYI   +4 more
doaj  

Prediction of limit drawing ratio in deep drawing process of Mg alloy AZ31 using Fuzzy Logic [PDF]

, 2022
Marina Maia Araripe, Francisco Elicivaldo Lima, Rômulo do Nascimento Rodrigues   +2 more
openalex   +1 more source