Results 51 to 60 of about 154,045 (307)

Photometric redshift estimation via deep learning

open access: yes, 2017
The need to analyze the available large synoptic multi-band surveys drives the development of new data-analysis methods. Photometric redshift estimation is one field of application where such new methods improved the results, substantially.
D'Isanto, Antonio, Polsterer, Kai Lars
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Cause Analysis of Seepage Disaster in Deep Foundation Pit of Metro Station in Karst Stratum

open access: yesChengshi guidao jiaotong yanjiu
Objective In-depth study should be made on the seepage stability during deep foundation pit excavation in water-rich karst stratum in consideration of the water inrush disaster at the side wall or bottom of the pit during excavation construction in water-
WANG Xiangqiu   +2 more
doaj   +1 more source

Numerical Simulation of Deep Foundation Pit Construction under Complex Site Conditions

open access: yesAdvances in Civil Engineering, 2021
Based on the deep foundation pit project of Laoguancun station of Wuhan rail transit line 16 and according to the engineering characteristics of the construction conditions and the site surrounding the environment, the method of combining field ...
Huifen Liu   +3 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Excavation Deformation Analysis of Foundation Pits and Its Influence on Surrounding Buildings

open access: yesRenmin Zhujiang, 2022
With the efficient use of urban space,the construction of new foundation pit projects is becoming more and more difficult,and the research on the excavation deformation of foundation pits and its impact on surrounding buildings is becoming more important.
CHENG Xinyu   +3 more
doaj  

The Chernobyl Reference Horizon (?) in the Greenland Ice Sheet [PDF]

open access: yes, 1989
Published reports of the presence of radioactive debris from the Chernobyl reactor accident in snow on the Greenland ice sheet raised the strong prospect that such debris might constitute a valuable time stratigraphic marker all over the ice sheet. Large
Dibb, Jack E.
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Construction Technology of Deep Foundation Pit Support in Municipal Civil Engineering Foundation Construction

open access: yesJournal of Architectural Research and Development, 2023
Municipal civil engineering is the key content of municipal construction, and the construction scale is usuallylarge. The quality of the project plays an important role in the development of urban economy. Due to the rapid increase of high-rise buildings, skyscrapers and underground buildings, the construction technology of deep foundation pit support ...
openaire   +1 more source

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