Results 1 to 10 of about 10,438 (257)

Tissue alkaline phosphatase activity and expression in an experimental infant swine model of cardiopulmonary bypass with deep hypothermic circulatory arrest [PDF]

Journal of Inflammation, 2020
Background Infant cardiac surgery with cardiopulmonary bypass results in decreased circulating alkaline phosphatase that is associated with poor postoperative outcomes.
Ludmila Khailova, Justin Robison, James Jaggers, Richard Ing, Scott Lawson, Amy Treece, Danielle Soranno, Suzanne Osorio Lujan, Jesse A. Davidson   +8 more
doaj   +7 more sources

Effect of Deep Hypothermic Circulatory Arrest Versus Moderate Hypothermic Circulatory Arrest in Aortic Arch Surgery on Postoperative Renal Function: A Systematic Review and Meta‐Analysis [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Moderate hypothermic circulatory arrest (MHCA) has been widely used in aortic arch surgery. However, the renal function after MHCA remains controversial. We performed a systematic review and meta‐analysis direct comparison of the postoperative
Liang Cao, Xiaoxiao Guo, Yuan Jia, Lijing Yang, Hongbai Wang, Su Yuan   +5 more
doaj   +4 more sources

Aortic Arch Replacement without Deep Hypothermic Circulatory Arrest [PDF]

Case Reports in Surgery, 2021
A 60-year-old man presented with a thoracic aortic aneurysm without rupture accompanied by severe nonrheumatic aortic valve insufficiency and unstable angina. Surgery was performed and included several steps: (1) resection and reconstruction of ascending
Zviad Bakhutashvili, Lia Janelidze, Kakhaber Beria, Simon Matikashvili, Eduard Limonjiani   +4 more
doaj   +5 more sources

Cannabinoid Receptor Agonist WIN55, 212-2 Attenuates Injury in the Hippocampus of Rats after Deep Hypothermic Circulatory Arrest [PDF]

Brain Sciences, 2023
Objectives: Postoperative neurological deficits remain a challenge in cardiac surgery employing deep hypothermic circulatory arrest (DHCA). This study aimed to investigate the effect of WIN55, 212-2, a cannabinoid agonist, on brain injury in a rat model ...
Ming-Huan Yu, Qin Yang, You-Peng Zhang, Jia-Hui Wang, Ren-Jian-Zhi Zhang, Zhi-Gang Liu, Xiao-Cheng Liu   +6 more
doaj   +4 more sources

Fontan procedure on deep hypothermic circulatory arrest: Short-term results and technique [PDF]

Annals of Pediatric Cardiology, 2022
Background : Various operative strategies are described for the Fontan procedure. In this study, we describe our short-term results and technique of Fontan procedure on cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA). Methods :
Dhananjay P Malankar, Shivaji Mali, Shyam Dhake, Amit Mhatre, Dilip Bind, Bharat Soni, Dinesh Kandavel, Jinil Raj, Parvez Patel, Swati Garekar   +9 more
doaj   +4 more sources

Consciousness in deep hypothermic circulatory arrest: a feasibility study [PDF]

Journal of Cardiothoracic Surgery
Background Studies have not explored consciousness during deep hypothermic circulatory arrest (DHCA). However, as studies in cardiac arrest have identified a spectrum of consciousness, we sought to establish the feasibility of studying consciousness ...
Joshua Ross, Thomas Jan, Deane Smith, Anelly Gonzales, Aubrey Galloway, Natalia Leontovich, Tara Keshavarz, Analise Dickinson, David Friedman, Emmeline Koopman, Elise Huppert, Ian Jaffe, Christopher Burke, John Kern, Paul Stelzer, Ashraf Sabe, Rebecca Spiegel, Andrew Klein, Arvind Rajagopal, Gage Parr, Charles Deakin, Sam Parnia   +21 more
doaj   +3 more sources

Incidence of postoperative seizures in neonates following cardiac surgery with regional cerebral perfusion and deep hypothermic circulatory arrestCentral MessagePerspective [PDF]

JTCVS Open, 2023
Objectives: Historically, our center has primarily used deep hypothermic circulatory arrest, but in recent years some surgeons have selectively used regional cerebral perfusion as an alternative.
Jill Hsia, MD, Nicholas S. Abend, MD, MSCE, J. William Gaynor, MD, Jonathan M. Chen, MD, Stephanie Fuller, MD, Katsuhide Maeda, MD, PhD, Constantine D. Mavroudis, MD, MSc, MTR, Muhammad Nuri, MD, Jan Leonard, MSPH, Steve B. Ampah, PhD, Daniel J. Licht, MD, Shavonne L. Massey, MD, MSCE, Maryam Y. Naim, MD, MSCE   +12 more
doaj   +2 more sources

Electroencephalography as a tool to predict cerebral oxygen metabolism during deep-hypothermic circulatory arrest in neonates with critical congenital heart diseaseCentral MessagePerspective [PDF]

JTCVS Open, 2023
Objectives: Recent research suggests that increased cerebral oxygen use during surgical intervention for neonates with congenital heart disease may play a role in the development of postoperative white matter injury.
Gerard H. Laurent, ScB, Tiffany S. Ko, PhD, Kobina G. Mensah-Brown, MD, MS, Constantine D. Mavroudis, MD, MSC, MTR, Marin Jacobwitz, CRNP, PhD, Nicolina Ranieri, BSc, Susan C. Nicolson, MD, J. William Gaynor, MD, Wesley B. Baker, PhD, Daniel J. Licht, MD, Shavonne L. Massey, MD, MSCE, Jennifer M. Lynch, MD, PhD   +11 more
doaj   +2 more sources

Transcriptome Profiling Reveals Activation of Inflammation and Apoptosis in the Neonatal Striatum After Deep Hypothermic Circulatory Arrest [PDF]

, 2019
Objectives: Brain injury, leading to long-term neurodevelopmental deficits, is a major complication in neonates undergoing cardiac surgeries. Because the striatum is one of the most vulnerable brain regions, we used mRNA sequencing to unbiasedly identify
Bittel, Douglas, Kibiryeva, Nataliya, Nigam, Vishal, Pastuszko, Anna, Pastuszko, Peter, Timms, Andrew E., Tu, Lan N   +6 more
core   +4 more sources

AdipoRon Inhibits Neuroinflammation Induced by Deep Hypothermic Circulatory Arrest Involving the AMPK/NF-κB Pathway in Rats [PDF]

Pharmaceutics, 2022
Deep hypothermic circulatory arrest (DHCA) can induce systemic inflammatory response syndrome, including neuroinflammation. Finding suitable compounds is necessary for attenuating neuroinflammation and avoiding cerebral complications following DHCA.
Weidong Yan, Sizhe Gao, Qiaoni Zhang, Jiachen Qi, Gang Liu, Yuan Teng, Jian Wang, Shujie Yan, Bingyang Ji   +8 more
doaj   +2 more sources