Results 31 to 40 of about 2,676,847 (166)

Use of Aprotinin in Patients Undergoing Deep Hypothermic Circulatory Arrest: A Review

, 2023
Hemostatic derangements continue to be a major clinical challenge during thoracic aortic surgery using deep hypothermic circulatory arrest despite advances in surgical and pharmacologic therapy.
Suzanne Huffman-Egger
core   +1 more source

Neuroprotective effects of erythropoietin during deep hypothermic circulatory arrest☆ [PDF]

European Journal of Cardio-Thoracic Surgery, 2010
Permanent mild-to-severe brain injury with neurologic sequelae remains a significant source of postoperative morbidity in cardiovascular surgery. There is increasing evidence that erythropoietin confers neuroprotective effects in various conditions of neuronal damage, such as hypoxia and cerebral ischaemia.
Mehdi, Givehchian, Rudi, Beschorner, Cornelius, Ehmann, Lydia, Frauenlob, Matthias, Morgalla, Bahram, Hashemi, Gerhard, Ziemer, Albertus M, Scheule   +7 more
openaire   +2 more sources

Regional low-flow perfusion improves neurologic outcome compared with deep hypothermic circulatory arrest in neonatal piglets [PDF]

, 2004
BackgroundRegional low-flow perfusion is an alternative to deep hypothermic circulatory arrest, but whether regional low-flow perfusion improves neurologic outcome after deep hypothermic circulatory arrest in neonates remains unknown.
Schears, Gregory, Myung, Richard J, Waibel, Robert J, DeCampli, William M, Ittenbach, Richard F, Petko, Matus, Judkins, Alexander R   +6 more
core   +1 more source

Outcomes of single-stage total arch replacement via clamshell incision

Journal of Cardiothoracic Surgery, 2011
Background Treatment of complex aortic pathologies involving the transverse arch with extensive involvement of the descending aorta remains a surgical challenge.
Ishizaka Toru, Satoh Hisashi, Iwasaki Hiroto, Matsuda Hikaru   +3 more
doaj   +1 more source

Incidence of postoperative seizures in neonates following cardiac surgery with regional cerebral perfusion and deep hypothermic circulatory arrest.

, 2023
OBJECTIVES: Historically, our center has primarily used deep hypothermic circulatory arrest, but in recent years some surgeons have selectively used regional cerebral perfusion as an alternative.
Ampah, Steve B, Mavroudis, Constantine D, Fuller, Stephanie, Abend, Nicholas S, Hsia, Jill, Gaynor, J William, Maeda, Katsuhide, Chen, Jonathan M, Naim, Maryam Y, Massey, Shavonne L, Nuri, Muhammad, Licht, Daniel J, Leonard, Jan   +12 more
core   +1 more source

Rat model of cardiopulmonary bypass for deep hypothermic circulatory arrest [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2011
Large animal cardiopulmonary bypass (CPB) models have disadvantages, such as cost, lack of methods for assessment of neurocognitive function, and difficulties with long-term recovery. As a result, rodent models have been developed. Previous rodent models have certain drawbacks, including irrelevance to human flows used clinically.
Waterbury, Tom, Clark, Thomas J., Niles, Scott, Farivar, Robert Saeid   +3 more
openaire   +2 more sources

Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance [PDF]

, 2011
OBJECTIVE: Moxifloxacin reduces infectious complications after cerebral damage, such as ischemia and stroke. This study investigated whether moxifloxacin treatment influences cerebral inflammation and improves cognitive outcome after cardiopulmonary ...
Blobner, M., Kees, Frieder, Kochs, Eberhard F., Manfred Blobner, Dertinger, Nadja, Bettina Jungwirth, Kellermann, Kristine, Jungwirt, B., Eberhard F. Kochs, Dertinger, N., Kellermann, K., Kristine Kellermann, Jungwirth, Bettina, Nadja Dertinger, Blobner, Manfred, Frieder Kees, Kochs, E. F.   +16 more
core   +2 more sources

Effect of intermittent deep hypothermic circulatory arrest on brain metabolism [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 1994
The effect of intermittent systemic reperfusion during deep hypothermic circulatory arrest was investigated in dogs to learn how the total arrest period may be prolonged. The animals were cooled on cardiopulmonary bypass to 18 degrees C and divided into the following three experimental groups: group I (n = 7), 60 minutes of uninterrupted circulatory ...
T, Kimura, R, Muraoka, Y, Chiba, A, Ihaya, K, Morioka   +4 more
openaire   +2 more sources

Higher hematocrit improves cerebral outcome after deep hypothermic circulatory arrest [PDF]

, 1996
Background: Various degrees of hemodilution are currently in clinical use during deep hypothermic circulatory arrest to counteract deleterious rheologic effects linked with brain injury by previous reports.
Miura, Takuya, Laussen, Peter C., Jonas, Richard A., Lidov, Hart G.W., du Plessis, Adre, Shum-Tim, Dominique, Shin'oka, Toshiharu   +6 more
core   +1 more source

The role of microglia in Neuroinflammation associated with cardiopulmonary bypass

Frontiers in Cellular Neuroscience
Cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA) are indispensable core techniques in cardiac surgery. Numerous studies have shown that cardiopulmonary bypass and deep hypothermic circulatory arrest are associated with the ...
Lingda Meng, Tianxiang Gu, Peng Yu, Zhiwei Zhang, Zhijing Wei   +4 more
doaj   +1 more source