Results 51 to 60 of about 7,756 (213)

Role of calcium desensitization in the treatment of myocardial dysfunction after deep hypothermic circulatory arrest [PDF]

, 2013
Introduction Rewarming from deep hypothermic circulatory arrest (DHCA) produces calcium desensitization by troponin I (cTnI) phosphorylation which results in myocardial dysfunction.
Faggian, Giuseppe, Giacomazzi, Alice, Hallström, Seth, Linardi, Daniele, Luciani, Giovanni, Mazzucco, Alessandro, Milani, Elisabetta, Rungatscher, Alessio, Scarabelli, Tiziano M, Tessari, Maddalena   +9 more
core   +3 more sources

Experimental study on coronary perfusion with selective brain cooling for direct aortic surgery [PDF]

, 1959
1. Retrograde coronary perfusion in combination with selective brain cooling by irrigation was investigated in dogs, in comparison with direct coronary artery perfusion. 2.
Hayashi, Naomi
core   +1 more source

The role of microglia in Neuroinflammation associated with cardiopulmonary bypass

Frontiers in Cellular Neuroscience
Cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA) are indispensable core techniques in cardiac surgery. Numerous studies have shown that cardiopulmonary bypass and deep hypothermic circulatory arrest are associated with the ...
Lingda Meng, Tianxiang Gu, Peng Yu, Zhiwei Zhang, Zhijing Wei   +4 more
doaj   +1 more source

A Technical Modification for Establishing Selective Antegrade Cerebral Perfusion during Pulmonary Endarterectomy

The Thoracic & Cardiovascular Surgeon Reports, 2016
Pulmonary endarterectomy (PEA) due to chronic thromboembolic pulmonary hypertension (CTEPH) is mainly performed in deep hypothermic circulatory arrest without additional cerebroprotective means.
Martin Czerny, Patrick von Samson, Bernward Passlick, Friedhelm Beyersdorf, Johannes Kroll   +4 more
doaj   +1 more source

Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition

Frontiers in Cardiovascular Medicine, 2023
Chronic thromboembolic pulmonary hypertension is a rare but life-threatening complication of long-term central venous catheters (CVC) in children. However, evidence in terms of potential treatment strategies and outcome data remains scarce.
Maja Hanuna, Joseph Pattathu, Joscha Buech, Joscha Buech, Christine Kamla, Nikolaus Kneidinger, Nikolaus Kneidinger, Juergen Behr, Juergen Behr, Katrin Milger, Katrin Milger, Tobias Veit, Tobias Veit, Marina Nagel, Jan Abicht, Robert Dalla-Pozza, Marcus Fischer, Andre Jakob, Matthias Hermann, Rene Schramm, Laura L. Rosenthal, Nikolaus Haas, Jürgen Hörer, Jürgen Hörer, Christian Hagl, Christian Hagl, Christian Hagl, Sebastian G. Michel, Sebastian G. Michel, Sebastian G. Michel, Sebastian G. Michel, Sebastian G. Michel   +31 more
doaj   +1 more source

Tumour Thrombi in the Suprahepatic Inferior Vena Cava: The Cardiothoracic Surgeons’ View [PDF]

, 2013
Background. Retroperitoneal tumours propagate intrathoracic caval tumour thrombi (ICTT) of which we consider two subgroups: ICTT-III (extracardiac) and ICTT-IV (intracardiac). Methods. Case series review. Results.
Ashrafian, H, Athanasiou, T, Protopapas, AD   +2 more
core   +3 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Deep Hypothermic Circulatory Arrest with Lung Perfusion/Ventilation in a Patient with Acute Type A Aortic Dissection

Case Reports in Medicine, 2012
A 50-year-old black male presented with acute type A aortic dissection. Surgical repair was performed under deep hypothermic circulatory arrest (DHCA) with lung perfusion/ventilation throughout the procedure.
Yiliam F. Rodriguez-Blanco, Lester Garcia, Tania Brice, Marco Ricci, Tomas A. Salerno   +4 more
doaj   +1 more source

Antegrade cerebral protection in thoracic aortic surgery: lessons from the past decade [PDF]

, 2017
Objective: Prolonged deep hypothermic circulatory arrest (DHCA) adversely affects outcome and quality of life in thoracic aortic surgery. Several techniques of antegrade cerebral perfusion are routinely used: bilateral selective antegrade cerebral ...
Aymard, Thierry, Carrel, Thierry, Clément, Michel, Czerny, Martin, Krähenbühl, Eva S., Reineke, David, Schmidli, Jürg, Stalder, Mario   +7 more
core  

Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon, Meng Gu, Ralph Hurd, Kirk Riemer, Frank Hanley, Daniel Spielman   +5 more
wiley   +1 more source