Results 11 to 20 of about 7,677 (196)

MicroRNA expression in the hippocampal CA1 region under deep hypothermic circulatory arrest [PDF]

Neural Regeneration Research, 2019
Using deep hypothermic circulatory arrest, thoracic aorta diseases and complex heart diseases can be subjected to corrective procedures. However, mechanisms underlying brain protection during deep hypothermic circulatory arrest are unclear.
Xiao-Hua Wang, Dong-Xu Yao, Xiu-Shu Luan, Yu Wang, Hai-Xia Liu, Bei Liu, Yang Liu, Lei Zhao, Xun-Ming Ji, Tian-Long Wang   +9 more
doaj   +2 more sources

Effect of Deep Hypothermic Circulatory Arrest Versus Moderate Hypothermic Circulatory Arrest in Aortic Arch Surgery on Postoperative Renal Function: A Systematic Review and Meta‐Analysis [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Moderate hypothermic circulatory arrest (MHCA) has been widely used in aortic arch surgery. However, the renal function after MHCA remains controversial. We performed a systematic review and meta‐analysis direct comparison of the postoperative
Liang Cao, Xiaoxiao Guo, Yuan Jia, Lijing Yang, Hongbai Wang, Su Yuan   +5 more
doaj   +2 more sources

Retrograde cerebral perfusion reduces embolic and watershed lesions after acute type a aortic dissection repair with deep hypothermic circulatory arrest [PDF]

Journal of Cardiothoracic Surgery
Background To assess whether retrograde cerebral perfusion reduces neurological injury and mortality in patients undergoing surgery for acute type A aortic dissection.
Jacob Ede, Karl Teurneau-Hermansson, Birgitta Ramgren, Marion Moseby-Knappe, Daniel Oudin Åström, Mårten Larsson, Johan Sjögren, Per Wierup, Shahab Nozohoor, Igor Zindovic   +9 more
doaj   +2 more sources

Effects of different doses of ulinastatin on organ protection of deep hypothermic circulatory arrest in rats [PDF]

Journal of Cardiothoracic Surgery
Background Deep hypothermic circulatory arrest (DHCA) can cause systemic inflammatory response (SIR) and ischemia-reperfusion (I/R) injury, potentially exacerbating organ failure. Ulinastatin (UTI) is a frequently employed anti-inflammatory medication in
Yuan Teng, Jing Wang, Zhiyuan Bo, Tianlong Wang, Yuan Yuan, Guodong Gao, Bingyang Ji, Qiang Hu   +7 more
doaj   +2 more sources

CircFRRS1 drives neuroinflammation through the miR-27a-3p/TLR4 pathway after deep hypothermic circulatory arrest [PDF]

Frontiers in Cellular Neuroscience
Neurologic injury remains a critical complication of deep hypothermic circulatory arrest (DHCA) in aortic arch surgery, with neuroinflammation driven by multiple factors in its pathogenesis.
Weidong Yan, Tianlong Wang, Shuai Zhang, Mingru Zhang, Jing Wang, Han Zhang, Jieru Zhang, Ziyu Xie, Bingyang Ji, Changwei Wei   +9 more
doaj   +2 more sources

Deep hypothermic circulatory arrest

Continuing Education in Anaesthesia Critical Care & Pain, 2010
The cardiopulmonary bypass (CPB) circuit must be primed with a fluid solution. The volume of prime required is either based on a standard empirically derived volume greater than a minimum safe priming volume, or may be guided by the patient's weight or body surface area. The initial hematocrit (HCT) achieved after initiation of CPB is determined by the
Sarah Conolly, Joseph E Arrowsmith, Andrew A Klein   +2 more
  +4 more sources

Intrathecal morphine in two patients undergoing deep hypothermic circulatory arrest during aortic surgery -A case report- [PDF]

Korean Journal of Anesthesiology, 2012
We retrospectively report the first use of intrathecal morphine prior to incision in two male patients undergoing a complex aortic reconstruction, who required complete circulatory arrest under deep hypothermia for intraoperative and postoperative pain ...
Rene Przkora, Tomas D. Martin, Philip J. Hess, Rama S. Kulkarni   +3 more
doaj   +1 more source

Transcriptome Profiling Reveals Activation of Inflammation and Apoptosis in the Neonatal Striatum After Deep Hypothermic Circulatory Arrest [PDF]

, 2019
Objectives: Brain injury, leading to long-term neurodevelopmental deficits, is a major complication in neonates undergoing cardiac surgeries. Because the striatum is one of the most vulnerable brain regions, we used mRNA sequencing to unbiasedly identify
Bittel, Douglas, Kibiryeva, Nataliya, Nigam, Vishal, Pastuszko, Anna, Pastuszko, Peter, Timms, Andrew E., Tu, Lan N   +6 more
core   +2 more sources

Correlation of Cerebral Microdialysis with Non-Invasive Diffuse Optical Cerebral Hemodynamic Monitoring during Deep Hypothermic Cardiopulmonary Bypass

Metabolites, 2022
Neonates undergoing cardiac surgery involving aortic arch reconstruction are at an increased risk for hypoxic-ischemic brain injury. Deep hypothermia is utilized to help mitigate this risk when periods of circulatory arrest are needed for surgical repair.
Tiffany S. Ko, Constantine D. Mavroudis, Emilie J. Benson, Rodrigo M. Forti, Richard W. Melchior, Timothy W. Boorady, Vincent C. Morano, Kobina Mensah-Brown, Yuxi Lin, Danielle Aronowitz, Jonathan P. Starr, Tami M. Rosenthal, Brandon C. Shade, Kellie L. Schiavo, Brian R. White, Jennifer M. Lynch, J. William Gaynor, Daniel J. Licht, Arjun G. Yodh, Wesley B. Baker, Todd J. Kilbaugh   +20 more
doaj   +1 more source

Deep hypothermic total circulatory arrest for internal carotid artery aneurysm extending into the cranium: experience from a developing country [PDF]

, 2010
Cardiopulmonary bypass is commonplace for acquired and congenital cardiac procedures. It has also stretched to facilitate complicated non-cardiac operations.
Fatimi, Saulat, Hidayat, Ijaz, Jabbar, Abid, Shahabuddin, Syed, Sophie, Ziad   +4 more
core   +2 more sources