Results 61 to 70 of about 8,736,056 (314)

Deep Learning in the Wild

open access: yes, 2018
Deep learning with neural networks is applied by an increasing number of people outside of classic research environments, due to the vast success of the methodology on a wide range of machine perception tasks. While this interest is fueled by beautiful success stories, practical work in deep learning on novel tasks without existing baselines remains ...
Thilo Stadelmann   +10 more
openaire   +3 more sources

Improved multiscale attention based deep learning approach for automated sugarcane leaf disease detection using BSRI data

open access: yesScientific Reports
Early and accurate detection of sugarcane leaf diseases is critical for improving crop productivity and reducing economic losses in the agricultural sector.  Timely interventions enable sustainable crop management and better resource use.
Jannatul Mauya   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

How deep learning works --The geometry of deep learning

open access: yesCoRR, 2017
16 pages, 13 ...
Xiao Dong, Jiasong Wu, Ling Zhou
openaire   +3 more sources

Development of a Japanese polygenic risk score model for amyloid-β PET imaging in Alzheimer’s disease

open access: yesAlzheimer’s Research & Therapy
Background The use of polygenic risk scores (PRS) for predicting disease risk in Japanese populations, particularly for dementia and related phenotypes, remains markedly unexplored.
Misato Kaishima   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Using web-based peer assessment in fostering deep learning in computer programming [PDF]

open access: yes, 2004
Active learning is considered by many academics as an important and effective learning strategy. Students can improve the quality of their work by developing their higher cognitive skills through reflection on their own ideas and practice of analytic and
Sitthiworachart, Jirarat, Joy, Mike
core  

Deep Learning Barcoding for Improved DNA Sequence Classification [PDF]

open access: yes, 2023
openThe introduction of DNA barcoding has significantly transformed species identification, utilizing short DNA sequences from a uniform region of the genome. However, the conventional methods of DNA barcoding often depend on manual analysis and struggle
ABDALLA, YAZZED HUSSEIN YOUNIS
core  

Identification and characterization of intracerebral hemorrhage events in elderly veterans with alzheimer’s disease in the veterans affairs healthcare system

open access: yesScientific Reports
Cerebral amyloid angiopathy (CAA) and hypertensive (HTN) small vessel disease are causes of spontaneous intracerebral hemorrhage (ICH). We identified ICH rates in patients with all-cause mild cognitive impairment (MCI) or Alzheimer’s disease (AD), and ...
Peter J. Morin   +11 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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