Results 81 to 90 of about 2,716,934 (278)

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Deep Learning in Chemistry

Journal of Chemical Information and Modeling, 2019
Machine learning enables computers to address problems by learning from data. Deep learning is a type of machine learning that uses a hierarchical recombination of features to extract pertinent information and then learn the patterns represented in the data.
Adam C. Mater, Michelle L. Coote
openaire   +3 more sources

Correlation Between Depression-Associated Genes and Cancer Types: Predicting Cancer Based on Mutation Frequencies

IEEE Access
This study examines the potential interconnection between genetic mutations frequently observed in various types of cancer and depression, aiming to elucidate shared genetic factors that may influence the etiology and treatment of both conditions ...
Fernando Patricio Carranco-Avila, Clayanela Zambrano-Caicedo, Jonathan Javier Loor-Duque, Ariana Deyaneira Jimenez-Narvaez, Ivan Galo Reyes-Chacon, Paulina Vizcaino, Isidro Rafael Amaro Martin, Manuel Eugenio Morocho-Cayamcela   +7 more
doaj   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

A Classifier Based on K-Nearest Neighbors Using Weighted Summation of Reconstruction Errors [PDF]

مجله مدل سازی در مهندسی
In this paper, a classifier is introduced based on the nearest neighbor classifier and the reconstruction error for data classification. In the proposed method, first, K nearest data points (neighbors) from each category in the training data are ...
Rassoul Hajizadeh, Mohammad Ali Hosseinzadeh   +1 more
doaj   +1 more source

Experimental observation on the seismic performance of reinforced concrete columns with a well-confined plastic hinge region

Scientific Reports
Seismic performance evaluation was conducted on eight circular reinforced concrete columns. Key design parameters for the columns included the number of longitudinal reinforcements, yield strength of reinforcements, vertical spacing of spirals, aspect ...
Do Hyung Lee, Sanh N. Tra, Dong Joo Kim, Kihak Lee   +3 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Predictive Modeling for Fetal Health: A Comparative Study of PCA, LDA, and KPCA for Dimensionality Reduction

IEEE Access
Pregnancy complications significantly impact maternal and fetal health, requiring accurate and timely diagnostic methods for life-saving interventions.
Ariana Deyaneira Jimenez-Narvaez, Victor David Casa Vaca, Jonathan Javier Loor-Duque, Isidro Rafael Amaro Martin, Ivan Galo Reyes-Chacon, Paulina Vizcaino, Manuel Eugenio Morocho-Cayamcela   +6 more
doaj   +1 more source