Results 71 to 80 of about 820,067 (303)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Correlation Between Depression-Associated Genes and Cancer Types: Predicting Cancer Based on Mutation Frequencies

IEEE Access
This study examines the potential interconnection between genetic mutations frequently observed in various types of cancer and depression, aiming to elucidate shared genetic factors that may influence the etiology and treatment of both conditions ...
Fernando Patricio Carranco-Avila, Clayanela Zambrano-Caicedo, Jonathan Javier Loor-Duque, Ariana Deyaneira Jimenez-Narvaez, Ivan Galo Reyes-Chacon, Paulina Vizcaino, Isidro Rafael Amaro Martin, Manuel Eugenio Morocho-Cayamcela   +7 more
doaj   +1 more source

A General Framework for Uncertainty Estimation in Deep Learning [PDF]

, 2020
Antonio Loquercio, Mattia Segu, Davide Scaramuzza   +2 more
openalex   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Experimental observation on the seismic performance of reinforced concrete columns with a well-confined plastic hinge region

Scientific Reports
Seismic performance evaluation was conducted on eight circular reinforced concrete columns. Key design parameters for the columns included the number of longitudinal reinforcements, yield strength of reinforcements, vertical spacing of spirals, aspect ...
Do Hyung Lee, Sanh N. Tra, Dong Joo Kim, Kihak Lee   +3 more
doaj   +1 more source

A Classifier Based on K-Nearest Neighbors Using Weighted Summation of Reconstruction Errors [PDF]

مجله مدل سازی در مهندسی
In this paper, a classifier is introduced based on the nearest neighbor classifier and the reconstruction error for data classification. In the proposed method, first, K nearest data points (neighbors) from each category in the training data are ...
Rassoul Hajizadeh, Mohammad Ali Hosseinzadeh   +1 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Classification of Breast Cancer Ultrasound Images with Deep Learning-Based Models [PDF]

, 2022
Fatih Uysal, Mehmet Murat Köse
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source