Results 31 to 40 of about 151,751 (261)
Advances in Multimedia, 2022 Context construction can more effectively put students into the scene and deepen their understanding of reading. The cultivation of students’ comprehensive language use ability is the key teaching activity that English major teachers pay attention to ...
Lihong Quan
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Implications of Using Spheroidal “Cone Model” CMEs in Solar‐Wind Models
Space WeatherSpace‐weather forecasting requires advanced prediction of the arrival time and properties of coronal mass ejections (CMEs) in near‐Earth space. Kinematic properties of CMEs close to the Sun—such as speed, direction and angular width—are routinely ...
M. J. Owens +7 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Digital Reading in the Context of Media-Critical Discourses
On_CultureWith the transformation of media in the context of digitization, reading is once again becoming a highly debated topic. Not only are fears being expressed that the end of the ‘Gutenberg Galaxy’ will set back the spread of reading as a cultural technique,
Susanne Düwell
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Application of Computer-aided Diagnosis System Based on Deep Learning in Rib Fracture Diagnosis
CT Lilun yu yingyong yanjiu, 2022 Objective: To investigate the application value of computer-aided diagnosis (CAD) system based on deep learning (DL) in rib fracture diagnosis. Methods: The CT images of 232 patients with chest trauma were analyzed retrospectively and the films were read
Shan XIONG +5 more
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
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The pleasures of deep reading [PDF]
BMJ, 2003 The competitors of the BMJ include Hollywood films, Manchester United, and a walk in the park. We live in the “attention economy” and compete desperately for a few moments of your time. There are so many other things to do apart from read the BMJ . Consequently many readers spend only a few minutes on the journal, flicking from Minerva to the news and ...
openaire +1 more source