Results 161 to 170 of about 204,461 (310)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The Hidden Persistence of Deep-Sea Pollution. [PDF]
Dachs J +8 more
europepmc +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Widespread deep-sea microorganisms in subseafloor geochemical cycling. [PDF]
Hageman RL +8 more
europepmc +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Crystallization Behavior of the Hydrogen Sulfide Hydrate Formed in Microcapillaries
Jiyue Sun +4 more
doaj +1 more source
Environmental Adaptation Strategies of Deep-Sea Fungi. [PDF]
Leng S, Liu CH.
europepmc +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The mystery evoked by the deep sea—its darkness, remoteness, and inaccessibility—has long captivated the public imagination. Iconic works of science fiction as well as pioneering documentaries reflect a fascination with unveiling the unknown; this spirit of discovery, of bringing light into the depths, remains alive today and has arguably even ...
openaire +1 more source

