Results 141 to 150 of about 4,061,607 (254)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Anthropogenic pollutants' threats to deep-sea ecosystems: Research challenges and technological frontiers. [PDF]

Eco Environ Health
Hou R, Feng JC, Zhang S.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Crystallization Behavior of the Hydrogen Sulfide Hydrate Formed in Microcapillaries

ACS Omega, 2021
Jiyue Sun, I-Ming Chou, Lei Jiang, Juezhi Lin, Rui Sun   +4 more
doaj   +1 more source

Deep Sea hydrothermal vent habitats support gravid Antarctic krill. [PDF]

Commun Biol
Bernard KS, Bernardino AF, Buck KN, Caprara S, Freiberger RB, Hogan E, Kaplan RL, Micallef A, Moore LE, Seabrook S, Thurber AR.   +10 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Corrigendum: N-terminus GTPase domain of the cytoskeleton protein FtsZ plays a critical role in its adaptation to high hydrostatic pressure

Frontiers in Microbiology
Xue-Hua Cui, Xue-Hua Cui, Yu-Chen Wei, Xue-Gong Li, Xue-Gong Li, Xiao-Qing Qi, Xiao-Qing Qi, Long-Fei Wu, Long-Fei Wu, Long-Fei Wu, Wei-Jia Zhang, Wei-Jia Zhang   +11 more
doaj   +1 more source

Portrayal of the deep sea: Haeckel's Atolla wyvillei, the challenger expedition, and the boundaries of science and illustration. [PDF]

Naturwissenschaften
Bock BL.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Hitch-hiking in the deep sea: Amphipods embrace sea spiders in the Southeast Pacific Ocean. [PDF]

Ecology
Pérez-Schultheiss J, Esquete P, Henningsen A, Soto E, Marlow J.   +4 more
europepmc   +1 more source