Results 141 to 150 of about 1,292,419 (308)

Exploring the Effects of Internal and External Factors on the Early Growth of Anchovy (Engraulis japonicus) in the Yellow Sea Based on Otolith Microstructure

open access: yesProgress in Fishery Sciences
The abundant and widely distributed resources of small pelagic fish in marine ecosystems constitute significant targets for commercial fisheries. The Japanese anchovy (Engraulis japonicus) is a prominent representative of small pelagic fish and is ...
Wenwen WANG   +6 more
doaj   +1 more source

Arctic coral reefs [PDF]

open access: yes, 2007
Recent expeditions to the cold, northern waters of the Arctic have revealed giant deep-sea coral reefs. In this article, Tina Kerby and Jason Hall-Spencer describe the latest findings from a project to study these surprising ...
Hall-Spencer, JM, Kerby, T
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Sea breeze: Induced mesoscale systems and severe weather [PDF]

open access: yes
Sea-breeze-deep convective interactions over the Florida peninsula were investigated using a cloud/mesoscale numerical model. The objective was to gain a better understanding of sea-breeze and deep convective interactions over the Florida peninsula using
Cotton, W. R.   +2 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Metagenome sequencing and 982 microbial genomes from Kermadec and Diamantina Trenches sediments

open access: yesScientific Data
Deep-sea trenches representing an intriguing ecosystem for exploring the survival and evolutionary strategies of microbial communities in the highly specialized deep-sea environments.
Yingdong Li   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Far O\u27er The Deep Blue Sea [PDF]

open access: yes
[Verse 1]The moon is beaming brightly love, Upon the deep blue seaA trusty crew is waiting near,For thee, dear girl, for thee!Then leave thy downy couch, my love, And with thy sailor flee;His gallant bark shall bear thee safe,Far o\u27er the deep blue ...
Hewitt, John H.   +1 more
core   +1 more source

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