Results 191 to 200 of about 5,166,382 (407)

Metagenome sequencing and 982 microbial genomes from Kermadec and Diamantina Trenches sediments

open access: yesScientific Data
Deep-sea trenches representing an intriguing ecosystem for exploring the survival and evolutionary strategies of microbial communities in the highly specialized deep-sea environments.
Yingdong Li   +3 more
doaj   +1 more source

Variance Component Estimation (VCE)-Based Adaptive Stochastic Modeling for Enhanced Convergence and Robustness in GNSS Precise Point Positioning (PPP)

open access: yesRemote Sensing
The stochastic model in Precise Point Positioning (PPP) defines the statistical properties of observations and the dynamic behavior of parameters. An inaccurate stochastic model can degrade positioning accuracy, ambiguity resolution, and other aspects of
Yanning Zheng   +4 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Sponge spicules in abyssal and bathyal sediments of the NE Atlantic [PDF]

open access: yes, 1993
Siliceous sponge spicules are concurrently mentioned in deep-sea expedition reports as constituents of abyssal and bathyal sediments, al though generally comprising only a few percent of the single ...
Barthel, Dagmar, Tendal, Ole
core  

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Hydrodynamics Model Identification and Model-Based Control Application of a New Type of AUV

open access: yesJournal of Marine Science and Engineering
The hydrodynamic coefficients of underwater robots can be used to evaluate their maneuverability and motion stability and to design motion controllers, thereby reducing experimental time and costs.
Lunyang Lin   +6 more
doaj   +1 more source

Arctic coral reefs [PDF]

open access: yes, 2007
Recent expeditions to the cold, northern waters of the Arctic have revealed giant deep-sea coral reefs. In this article, Tina Kerby and Jason Hall-Spencer describe the latest findings from a project to study these surprising ...
Hall-Spencer, JM, Kerby, T
core   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Deep Uncertainty Surrounding Coastal Flood Risk Projections: A Case Study for New Orleans

open access: yes, 2017
Future sea-level rise drives severe risks for many coastal communities. Strategies to manage these risks hinge on a sound characterization of the uncertainties. For example, recent studies suggest that large fractions of the Antarctic ice sheet (AIS) may
Keller, Klaus, Wong, Tony E.
core   +1 more source

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