Results 221 to 230 of about 1,292,419 (308)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

A Method for the Intelligent Identification of the Operating Conditions of Deep-Sea Submersibles and Its Application. [PDF]

Sensors (Basel)
Zhang Y, Li Z, Tang J, He K.
europepmc   +1 more source

Phosphorescence in the Deep Sea [PDF]

Science, 1884
openaire   +2 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Pathogenic effects of <i>Halomonas</i> on cyanobacteria and biocontrol potential of a deep-sea <i>Bacillus</i> strain. [PDF]

Appl Environ Microbiol
Li X, Yuan M, Sun C, Wu S.
europepmc   +1 more source

Light in the deep sea [PDF]

Science, 1884
openaire   +3 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Omics exploration of deep-sea biodiversity: data from the "Pourquoi Pas les Abysses?" and eDNAbyss projects. [PDF]

Sci Data
Arnaud-Haond S, Trouche B, Liautard-Haag C, Alain K, Aubé J, Bonhomme F, Brandt MI, Caillarec-Joly A, Cambon MA, Cornette F, Cueff-Gauchard V, Durand P, de Vargas C, Felix C, Fuchs S, Genoscope Technical Team, Günther B, Henry N, Hourdez S, Jollivet D, Le Port AS, Lesongeur F, Maignien L, Comtet-Marre S, Matabos M, Omnes E, Peyret P, Pradillon F, Sarrazin J, Schauberger C, Tran Lu Y A, Ulloa O, Vaz S, Zeppili D, Viard F, Gavory F, Gaz S, Guy J, Jacoby E, Oliveira PH, Samson G, Aury JM, Wincker P, Pesant S, Poulain J, Belser C.   +45 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

The false promise of deep-sea mining. [PDF]

NPJ Ocean Sustain
Alger J, Green JF, Neville KJ, Park S, VanDeveer SD, Webster DG.   +5 more
europepmc   +1 more source