Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
PWE-206 Propofol deep sedation for elderly patients: a comparison between EUS with or without fine needle aspiration procedure [PDF]
, 2012 Somchai Amornyotin +2 more
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
PWE-131 Propofol deep sedation for small bowel enteroscopy in elderly patients in a world gastroenterology organising endoscopy training center in Thailand [PDF]
, 2012 Somchai Amornyotin, Siriporn Kongphlay
openalex +1 more source
Ultrasound-Guided Pudendal Nerve Block Combined with Propofol Deep Sedation versus Spinal Anesthesia for Hemorrhoidectomy: A Prospective Randomized Study [PDF]
, 2021 Jian He +7 more
openalex +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Validation of the Bispectral Index Monitor During Conscious and Deep Sedation in Children
, 2003 Nicole Brown McDermott +3 more
openalex +1 more source
Deep Sedation or General Anesthesia for ERCP? [PDF]
, 2013 Nirav Thosani, Subhas Banerjee
openalex +1 more source
Continuous Deep Sedation until Death in Neonates and Infants in Flanders: A Post-Mortem Survey [PDF]
, 2021 Laure Dombrecht +7 more
openalex +1 more source