Results 231 to 240 of about 240,068 (314)

Table S12 from Deep-Learning Model for Tumor-Type Prediction Using Targeted Clinical Genomic Sequencing Data

Madison Darmofal, Shalabh Suman, Gurnit Atwal, Michael Toomey, Jie‐Fu Chen, Jason C. Chang, Efsevia Vakiani, Anna M. Varghese, Anoop Balakrishnan Rema, Aijazuddin Syed, Nikolaus Schultz, Michael F. Berger, Quaid Morris   +12 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

“Big Events” and HIV Transmission Dynamics: Estimating Time Since HIV Infection from Deep Sequencing Data Among Sex Workers and Their Clients in Dnipro, Ukraine [PDF]

Viruses
Cholette F, Herpai N, McClarty L, Balakireva O, Pavlova D, Lopatenko A, Capiña R, Sandstrom P, Pickles M, Forget E, Mishra S, Becker M.   +11 more
europepmc   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Detection of fungal sequences in human brain: rDNA locus amplification and deep sequencing. [PDF]

Sci Rep
Leitao R, Wan IU, Chown H, Williams TJ, Fisher MC, Rhodes J.   +5 more
europepmc   +1 more source

Deep RNA Sequencing Reveals Hidden Features and Dynamics of Early Gene Transcription in Paramecium bursaria Chlorella Virus 1

, 2014
Guillaume Blanc, Michael Mozar, Irina V. Agarkova, James R. Gurnon, Giane M. Yanai-Balser, Janet M. Rowe, Yuannan Xia, Jean-Jack M. Riethoven, David D. Dunigan, James L. Van Etten   +9 more
openalex   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Microdiversity of Deep-Sea <i>Bacillales</i> Isolated from Tyrrhenian Sea Sediments as Revealed by ARISA, 16S rRNA Gene Sequencing and BOX-PCR Fingerprinting

, 2013
Besma Ettoumi, Amel Guesmi, Lorenzo Brusetti, Sara Borin, Afef Najjari, Abdellatif Boudabous, Ameur Chérif   +6 more
openalex   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Investigation of Natural Resistance to Fostemsavir and Lenacapavir in Naïve Primary Infections by Ultra-Deep Sequencing of near Full-Length HIV-1 Genomes. [PDF]

Viruses
Lazzari E, Rozera G, Gagliardini R, Mazzotta V, Fabeni L, Forbici F, Berno G, Cosentino C, Girardi E, Antinori A, Maggi F, Abbate I.   +11 more
europepmc   +1 more source