Results 101 to 110 of about 471,556 (267)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Existence of Electrostatic Ion Cyclotron Waves in a Laboratory Created E Region Ionospheric‐Like Plasma

Geophysical Research Letters
Molecular ions are relatively cold in the E region ionosphere; however, they can upwell to the magnetosphere during geomagnetically active times. Resonance between electrostatic ion cyclotron (EIC) waves is a potential pathway to energize molecular ions.
Yu Liu, Rong Jin, Minchi Li, Wenlong Huang, Kexin Huang, Junnan Jiang, Pengcheng Yu, Jiuhou Lei   +7 more
doaj   +1 more source

Evaluation of deep space exploration risks and mitigations against radiation and microgravity. [PDF]

Front Nucl Med, 2023
Dobney W, Mols L, Mistry D, Tabury K, Baselet B, Baatout S.   +5 more
europepmc   +1 more source

Deep Learning in Cinematic Space

This short essay is an attempt to question the power we attribute to technology by drawing potentially new connections between the use of Artificial Intelligences in Stanley Kubrick’s 2001, A Space Odyssey and contemporary usages of artificial intelligences like ‘The Innovation Engine’. Kubrick gave us a warning. The subject of artificial intelligences,
openaire   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Nourishing the brain on deep space missions: nutritional psychiatry in promoting resilience. [PDF]

Front Neural Circuits, 2023
Pathare NN, Fayet-Moore F, Fogarty JA, Jacka FN, Strandwitz P, Strangman GE, Donoviel DB.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

A Substorm‐Dependent Negative Limit of Non‐Eclipse Surface Charging of a Chinese Geosynchronous Satellite

Space Weather
Surface charging is one of the most common causes of spacecraft anomalies. When and to what potential the spacecraft is charged are two important questions in space weather.
Zhiyi Fu, Zhenpeng Su, Bin Miao, Zhiyong Wu, Yiren Li, Kai Liu, Xu Shan, Yuming Wang   +7 more
doaj   +1 more source

3D Discrete element method modeling of the cone penetration test in lunar regolith simulant with various internal friction angles

Geo-spatial Information Science
The mechanical behavior of lunar regolith is highly influenced by its diverse mechanical properties, which are critical for geotechnical engineering activities during lunar exploration missions.
Siji Sanlang, Chao Wang, Xiaohua Tong, Huan Xie, Yongjiu Feng, Jia Li, Mingjing Jiang, Xiong Xu, Yanmin Jin   +8 more
doaj   +1 more source