Results 101 to 110 of about 798,589 (237)

Capabilities Development: From International Space Station and the Moon to Mars [PDF]

open access: yes
The President of the United States, in signing Space Policy Directive-1, directed the NASA Administrator to lead an innovative and sustainable program of exploration with commercial and international partners to enable human expansion across the solar ...
Boggs, Kathleen Gallagher   +2 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

BioSentinel: A Biological CubeSat for Deep Space Exploration. [PDF]

open access: yesAstrobiology, 2023
Massaro Tieze S   +3 more
europepmc   +1 more source

NASA's In-Space Propulsion Technology Program: A Step Toward Interstellar Exploration [PDF]

open access: yes, 2005
NASA's In-Space Propulsion Technology Program is investing in technologies that have the potential to revolutionize the robotic exploration of deep space.
Baggett, Randy   +3 more
core   +1 more source

Extra-terrestrial construction processes - advancements, opportunities and challenges

open access: yes, 2017
Government space agencies, including NASA and ESA, are conducting preliminary studies on building alternative space-habitat systems for deep-space exploration.
Anand, Mahesh   +3 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Payload Accommodations in NASA's Space Launch System, Block 1 and Beyond [PDF]

open access: yes
As part of NASA's new deep space exploration system, the Space Launch System (SLS) will provide the United States with guaranteed access to deep space and an unparalleled capability for launching primary and co-manifested payloads beyond Earth's orbit ...
Perry, Beverly A.   +2 more
core   +1 more source

CHARACTERIZATION OF OUTER SPACE RADIATION INDUCED CHANGES IN EXTREMOPHILES UTILIZING DEEP SPACE GATEWAY OPPORTUNITIES. [PDF]

open access: yes, 2018
Early integration of science and exploration concerns into the design of the Deep Space Gateway (DSG) is essential to maximizing its science and exploration potential.
Laundry, K.   +5 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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