Results 101 to 110 of about 7,150,509 (282)

Sleep disruption, use of sleep-promoting medication and circadian desynchronization in spaceflight crewmembers: Evidence in low-Earth orbit and concerns for future deep-space exploration missions. [PDF]

Sleep Med X, 2023
Albornoz-Miranda M, Parrao D, Taverne M.
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Energy Conversion Associated with Intermittent Currents in the Magnetosheath Downstream of the Quasi-Parallel Shock

Magnetochemistry
Using the data from the Magnetospheric Multiscale (MMS) mission, we studied the energy conversion between electromagnetic fields and particles (ions and electrons) in a spacecraft rest frame inside a turbulent magnetosheath downstream of the quasi ...
Xinmin Li, Rongsheng Wang, San Lu, Ao Guo, Zhijian Zhang   +4 more
doaj   +1 more source

Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration. [PDF]

Cell, 2021
Afshinnekoo E, Scott RT, MacKay MJ, Pariset E, Cekanaviciute E, Barker R, Gilroy S, Hassane D, Smith SM, Zwart SR, Nelman-Gonzalez M, Crucian BE, Ponomarev SA, Orlov OI, Shiba D, Muratani M, Yamamoto M, Richards SE, Vaishampayan PA, Meydan C, Foox J, Myrrhe J, Istasse E, Singh N, Venkateswaran K, Keune JA, Ray HE, Basner M, Miller J, Vitaterna MH, Taylor DM, Wallace D, Rubins K, Bailey SM, Grabham P, Costes SV, Mason CE, Beheshti A.   +37 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Ion and electron motions in the outer electron diffusion region of collisionless magnetic reconnection

Earth and Planetary Physics
Two-dimensional particle-in-cell simulations are performed to study the coupling between ion and electron motions in collisionless magnetic reconnection. The electron diffusion region (EDR), where the electron motions are demagnetized, is found to have a
Cong Chang, QuanMing Lu, San Lu, Kai Huang, RongSheng Wang   +4 more
doaj   +1 more source

A High-Accuracy, High Anti-Noise, Unbiased Frequency Estimator Based on Three CZT Coefficients for Deep Space Exploration Mission. [PDF]

Sensors (Basel), 2022
Lu W, Chen L, Wang Z, Cao J, Ren T.
europepmc   +1 more source

Exploring the Fractal Space of Sparse Deep Neural Network

IEEE Access
Sparse deep neural networks (DNNs) are preferable in many real-world applications, especially edge computing. How to find the sparse structure of deep neural networks so that the model can achieve better performance is an important research topic. Under the same sparsity level, the connection patterns of DNNs significantly affect their performance.
Hang Xu, Zhuangzhi Chen, Jinhuan Wang, Shanqing Yu, Dongwei Xu, Qi Xuan 0001   +5 more
openaire   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Seismic visibility of carbonated subducted oceanic crust in the lower mantle

Communications Earth & Environment
Seismological studies have previously detected abundant scatterers in the lower mantle, potentially linked to long-term slab subduction, and petrology studies suggest carbonates can be sequestrated within the oceanic crust and transported into the lower ...
Yajie Zhao, Xin Deng, Wenzhong Wang, Zhongqing Wu, Ye Yuan   +4 more
doaj   +1 more source