Results 101 to 110 of about 91,562 (307)

50kg-class Deep Space Exploration Technology Demonstration Micro-spacecraft PROCYON

, 2014
University of Tokyo and Japan Aerospace Exploration Agency (JAXA) are developing a 50kg-class microspacecraft named “PROCYON” for deep space exploration.
Kawakatsu, Yasuhiro, Funase, Ryu, Nakasuka, Shinichi, Fukushima, Yosuke, Tomiki, Atsushi, Kobayashi, Yuta, Nakatsuka, Junichi, Mita, Makoto, Kobayashi, Daisuke, Nonomura, Taku, Koizumi, Hiroyuki   +10 more
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

RADIATION MEASUREMENTS AND DOSIMETRY FOR DEEP-SPACE EXPLORATION [PDF]

, 2018
Dosimetry and radiation monitoring are key factors for the planning of future human exploration on deep-space missions outside of Low-Earth Orbit (LEO), as radiation exposure poses one of the major health risks for astronauts in deep space.
Burmeister, Sönke, Matthiä, Daniel, Reitz, Guenther, Rafkin, Scot, Appel, Jan Kristoffer, Ehresmann, Bent, Lohf, Henning, Hassler, Donald M., Guo, Jingnan, Wimmer-Schweingruber, Robert, Zeitlin, Cary, Berger, Thomas   +11 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Human behavior and performance in deep space exploration: next challenges and research gaps. [PDF]

NPJ Microgravity, 2023
Pagnini F, Manzey D, Rosnet E, Ferravante D, White O, Smith N.   +5 more
europepmc   +1 more source

Space Medicine: Challenges for Deep Space Exploration

Journal of the Australasian Society of Aerospace Medicine
Abstract NASA’s Artemis program represents a critical step in humanity’s return to the Moon and future crewed missions to Mars. Artemis missions aim to test and develop the systems, habitats, and human performance strategies required for sustained space exploration.
openaire   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Musculoskeletal research in human space flight - unmet needs for the success of crewed deep space exploration. [PDF]

NPJ Microgravity, 2023
Liphardt AM, Fernandez-Gonzalo R, Albracht K, Rittweger J, Vico L.   +4 more
europepmc   +1 more source

The Deep Space Network: A Radio Communications Instrument for Deep Space Exploration

, 1983
The primary purpose of the Deep Space Network (DSN) is to serve as a communications instrument for deep space exploration, providing communications between the spacecraft and the ground facilities.
Slobin, S. D., Armstrong, J. W., Petty, S. M., Stelzried, C. T., Kinman, P. W., Donnelly, H., Trowbridge, D. L., Noreen, G. K., Renzetti, N. A., Burow, N. A.   +9 more
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source