Results 111 to 120 of about 798,589 (237)

Deep Space Habitability Design Guidelines Based on the NASA NextSTEP Phase 2 Ground Test Program [PDF]

open access: yes
This report summarizes habitation design guidelines for deep space habitats, which were derived from the NASA Next Space Technologies for Exploration Partnerships (NextSTEP) Phase 2 Habitat Ground Test Program.
Beaton, Kara   +6 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Were Gravity Waves or Lamb Waves Responsible for the Large‐Scale Thermospheric Response to the Tonga Eruption?

open access: yesAGU Advances
The extraordinary eruption of the Tonga volcano on 15 January 2022 lofted material to heights exceeding 50 km, marking the highest observed since the satellite era.
Ruoxi Li   +6 more
doaj   +1 more source

NASA's Space Launch System Moves into Testing and Integration [PDF]

open access: yes
NASA's Space Launch System (SLS) has moved from design and manufacturing into testing and integration for its first flight in fiscal year 2020. In 2017, the NASA/industry team completed manufacturing of all major structural elements for the launch ...
Creech, Steve, Honeycutt, John
core   +1 more source

SchNet: A continuous-filter convolutional neural network for modeling quantum interactions [PDF]

open access: yes, 2017
Deep learning has the potential to revolutionize quantum chemistry as it is ideally suited to learn representations for structured data and speed up the exploration of chemical space. While convolutional neural networks have proven to be the first choice
Chmiela, Stefan   +5 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

NASAs Space Launch System: Launch Capability for Lunar Exploration and Transformative Science [PDF]

open access: yes
Excitement is building for the first launch of NASAs Space Launch System (SLS), a unique exploration asset for the agencys Artemis lunar program as well as for a new generation of science missions.
Creech, Stephen D.
core   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster   +11 more
wiley   +1 more source

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