Results 51 to 60 of about 798,589 (237)

S-CANDELS: The Spitzer-Cosmic Assembly Near-Infrared Deep Extragalactic Survey. Survey Design, Photometry, and Deep IRAC Source Counts [PDF]

, 2015
The Spitzer-Cosmic Assembly Deep Near-Infrared Extragalactic Legacy Survey (S-CANDELS; PI G. Fazio) is a Cycle 8 Exploration Program designed to detect galaxies at very high redshifts (z > 5).
Ashby, M. L. N., Dunlop, J. S., Egami, E., Faber, S. M., Fazio, G. G., Ferguson, H. C., Grogin, N. A., Hora, J. L., Huang, J. -S., Koekemoer, A. M., Labbe, I., Wang, Z., Willner, S. P.   +12 more
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Geological characteristics of Chang’E-6 landing area in micro-scale unveiled by new observation data

Nature Communications
Chang’E-6 mission successfully achieved humanity’s first sample return from the farside of the Moon. Here, we report a high-precision terrain dataset with millimeter-to-decimeter spatial resolution around the CE-6 landing site. Based on this dataset, the
Wei Yan, Xingguo Zeng, Xin Ren, Wangli Chen, Xingye Gao, Wei Zuo, Bin Liu, Zhoubin Zhang, Qiang Fu, Jianjun Liu, Chunlai Li   +10 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Simulating Atmospheric Dust With a Global Variable‐Resolution Model: Model Description and Impacts of Mesh Refinement

Journal of Advances in Modeling Earth Systems, 2023
In this study, a global variable‐resolution modeling framework of atmospheric dust and its radiative feedback is established and evaluated. In this model, atmospheric dust is simulated simultaneously with meteorological fields, and dust‐radiation ...
Jiawang Feng, Chun Zhao, Qiuyan Du, Mingyue Xu, Jun Gu, Zhiyuan Hu, Yu Chen   +6 more
doaj   +1 more source

Integrated Atmosphere Resource Recovery and Environmental Monitoring Technology Demonstration for Deep Space Exploration [PDF]

, 2012
Exploring the frontiers of deep space continues to be defined by the technological challenges presented by safely transporting a crew to and from destinations of scientific interest.
Abney, Morgan B., Jan, Darrell L., Knox, James C., Parrish, Keith J., Perry, Jay L., Roman, Monserrate C.   +5 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Anomaly Detection Method for Harmonic Reducers with Only Healthy Data

Sensors
A harmonic reducer is an important component of industrial robots. In practical applications, it is difficult to obtain enough anomaly data from error cases for the supervised training of models.
Yuqing Li, Linghui Zhu, Minqiang Xu, Yunzhao Jia   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source