Results 31 to 40 of about 2,478,930 (305)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Rock dynamic strength prediction in cold regions using optimized hybrid algorithmic models

open access: yesGeomechanics and Geophysics for Geo-Energy and Geo-Resources
Predicting the dynamic mechanical characteristics of rocks during freeze–thaw cycles (FTC) is crucial for comprehending the damage process of FTC and averting disasters in rock engineering in cold climates.
You Lv   +10 more
doaj   +1 more source

Water withdrawal from deep soil layers: a key strategy to sustain growth during dry seasons in tropical Eucalyptus plantations [PDF]

open access: yes, 2013
Little is known about the role of very deep roots to supply the water requirements of tropical forests. Clonal Eucalyptus plantations managed in short rotation on very deep Ferralsols are simple forest ecosystems (only 1 plant genotype growing on a ...
Bouillet, Jean-Pierre   +8 more
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

An additional deep-water mass in Drake Passage as revealed by 3He data [PDF]

open access: yes, 2003
We present 3He data froma repeat section across Drake Passage, fromthree sections off the South American continent in the Pacific, at 28?S, 35?S, and 43?S, and fromthree sections in the Atlantic, eastward of the Malvinas, close to 35?W, and near the ...
Arhan   +36 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

An Approach to Predicting Sediment Microbial Fuel Cell Performance in Shallow and Deep Water

open access: yesApplied Sciences, 2018
Here we present an approach to predicting sediment microbial fuel cell performance based on environmental conditions. Sediment total organic carbon and water temperature were found to be important determinants in predicting the power output from ...
Kenneth E. Richter, Jennifer M. Ayers
doaj   +1 more source

Metabolic Tolerance to Atmospheric Pressure of Two Freshwater Endemic Amphipods Mostly Inhabiting the Deep-Water Zone of the Ancient Lake Baikal

open access: yesInsects, 2022
Lake Baikal is the only freshwater reservoir inhabited by deep-water fauna, which originated mostly from shallow-water ancestors. Ommatogammarus flavus and O. albinus are endemic scavenger amphipods (Amphipoda, Crustacea) dwelling in wide depth ranges of
Ekaterina Madyarova   +8 more
doaj   +1 more source

Water uptake in deep soil layers by tropical eucalypt plantations: consequences for water resources under climate change. [P117] [PDF]

open access: yes, 2015
Climate models predict that the frequency, intensity and duration of drought events will increase in tropical regions. Questions such as how planted forests will adapt to future constraints on water availability have broad implications for the supply of ...
Bouillet, Jean-Pierre   +6 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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