Results 51 to 60 of about 10,020,504 (351)

Numerical Analysis of Bismuth Telluride-Based Thermoelectric Device Performance in Lunar Extreme Cold Environments

Energies
As lunar exploration missions advance, the need for safe and sustainable in situ energy systems has become increasingly critical. This study investigates the thermoelectric performance of Bi2Te3-based thermoelectric materials under the natural ...
Xin Xu, Jiaxin Zheng, Licheng Sun, Xiting Long, Tianyi Gao, Biao Li, Qinyi Zhang, Cunbao Li, Jun Wang, Zhengyu Mo, Min Du, Heping Xie   +11 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Development of a 140 MPa Deep In Situ Pressure-Preserved Coring Controller

Applied Sciences
Deep in situ pressure coring provides an accurate means of determining oil and gas reserve parameters. The key to achieving pressure coring at depths exceeding 5000 m lies in the ultimate bearing strength and stability of the pressure controllers. Due to
Cong Li, Xiaojun Shi, Le Zhao, Xin Fang, Xun Yang, Jianan Li   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Hydrodynamic Performance Study of a Reciprocating Plate Column Dirven by Electro-permanent Magnet Technology

Machines
The reciprocating plate column is a kind of column with the plates driven by a geared motor, and it has advantages in regard to efficiency compared to traditional columns in the extraction process, however, it comes with an increase in energy consumption.
Kai Guo, Jianxu Jiang, Deqiang Zhang, Linyuan Meng, Yiran Zhang, Xiantao Fan, Hongsheng Zhang   +6 more
doaj   +1 more source

Prediction of Water Level and Water Quality Using a CNN-LSTM Combined Deep Learning Approach

, 2020
A Convolutional Neural Network (CNN)-Long Short-Term Memory (LSTM) combined with a deep learning approach was created by combining CNN and LSTM networks simulated water quality including total nitrogen, total phosphorous, and total organic carbon.
Sang-Soo Baek, J. Pyo, J. Chun
semanticscholar   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Architecture and reservoir quality of low-permeable Eocene lacustrine turbidite sandstone from the Dongying Depression, East China

Open Geosciences, 2018
The architecture and quality of lacustrine turbidites that act as petroleum reservoirs are less well documented. Reservoir architecture and multiscale heterogeneity in turbidites represent serious challenges to production performance.
Munawar Muhammad Jawad, Lin Chengyan, Chunmei Dong, Zhang Xianguo, Zhao Haiyan, Xiao Shuming, Azeem Tahir, Zahid Muhammad Aleem, Ma Cunfei   +8 more
doaj   +1 more source

The Effect of Water upon Deep Eutectic Solvent Nanostructure: An Unusual Transition from Ionic Mixture to Aqueous Solution

Angewandte Chemie, 2017
The nanostructure of a series of choline chloride/urea/water deep eutectic solvent mixtures was characterized across a wide hydration range by neutron total scattering and empirical potential structure refinement (EPSR). As the structure is significantly
O. Hammond, D. Bowron, K. Edler
semanticscholar   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source