Results 31 to 40 of about 10,020,504 (351)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Rock dynamic strength prediction in cold regions using optimized hybrid algorithmic models
Geomechanics and Geophysics for Geo-Energy and Geo-ResourcesPredicting the dynamic mechanical characteristics of rocks during freeze–thaw cycles (FTC) is crucial for comprehending the damage process of FTC and averting disasters in rock engineering in cold climates.
You Lv +10 more
doaj +1 more source
North Atlantic Deep Water Production during the Last Glacial Maximum
Nature Communications, 2016 Changes in deep ocean ventilation are commonly invoked as the primary cause of lower glacial atmospheric CO2. The water mass structure of the glacial deep Atlantic Ocean and the mechanism by which it may have sequestered carbon remain elusive.
J. Howe +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Experiment and Calculation Method of the Dynamic Response of Deep Water Bridge in Earthquake
Latin American Journal of Solids and StructuresFor deep-water long span bridges under earthquakes, the interaction between water and structure will inevitably induce the hydrodynamic force on the structures.
Yue Li, Zhi Li, Qiqi Wu
doaj +1 more source
NUMERICAL PREDICTION OF SOLITARY WAVE FORMATION OF A PLANING HULL IN SHALLOW WATER CHANNELS
Brodogradnja, 2020 This paper uses a CFD (Computational Fluid Dynamics) analysis to investigate the shallow water effects on prismatic planing hull. The turbulence flow around the hull was described by Reynolds Navier Stokes equations RANSE using the k-ɛ turbulence model ...
Tamer M. Ahmed +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Journal of Marine Science and EngineeringConsidering that the information contained in the interference structure of the “target-receiver” path in active sonar is crucial for remote sensing of the target position or the environmental information, this paper studies the method for coherent ...
Jincong Dun +4 more
doaj +1 more source
An Approach to Predicting Sediment Microbial Fuel Cell Performance in Shallow and Deep Water
Applied Sciences, 2018 Here we present an approach to predicting sediment microbial fuel cell performance based on environmental conditions. Sediment total organic carbon and water temperature were found to be important determinants in predicting the power output from ...
Kenneth E. Richter, Jennifer M. Ayers
doaj +1 more source