Results 121 to 130 of about 716,083 (340)

Aβ-induced vulnerability propagates via the brain’s default mode network

Nature Communications, 2019
Amyloid-β (Aβ) deposition occurs in Alzheimer's disease but its relation to disease features such as local brain hypometabolism or cognitive decline is unclear.
Tharick A. Pascoal, Sulantha Mathotaarachchi, Min Su Kang, Sara Mohaddes, Monica Shin, Ah Yeon Park, Maxime J. Parent, Andrea L. Benedet, Mira Chamoun, Joseph Therriault, Heungsun Hwang, A. Claudio Cuello, Bratislav Misic, Jean-Paul Soucy, John A. D. Aston, Serge Gauthier, Pedro Rosa-Neto   +16 more
doaj   +1 more source

Task-load-dependent activation of dopaminergic midbrain areas in the absence of reward [PDF]

, 2011
Dopamine release in cortical and subcortical structures plays a central role in reward-related neural processes. Within this context, dopaminergic inputs are commonly assumed to play an activating role, facilitating behavioral and cognitive operations ...
Böhler, Nico, Heinze, Hans-Jochen, Hopf, Jens-Max, Krebs, Ruth, Noesselt, Toemme, Schoenfeld, Mircea A, Stoppel, Christian M   +6 more
core   +2 more sources

Resting State Abnormalities of the Default Mode Network in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis

Journal of Alzheimer's Disease, 2019
Background: Large-scale brain networks such as the default mode network (DMN) are often disrupted in Alzheimer’s disease (AD). Numerous studies have examined DMN functional connectivity in those with mild cognitive impairment (MCI), a presumed AD ...
L. Eyler, J. Elman, S. Hatton, S. Gough, Anna K Mischel, D. Hagler, C. Franz, Anna R. Docherty, C. Fennema-Notestine, N. Gillespie, D. Gustavson, M. Lyons, M. Neale, M. Panizzon, A. Dale, W. Kremen   +15 more
semanticscholar   +1 more source

[Default mode network and Alzheimer's disease].

Revista medica de Chile, 2013
mbehrens@redclinicauchile ...
Vergara E, Fernando, Behrens, Maria Isabel   +1 more
openaire   +3 more sources

Dynamic Control of Synaptic Plasticity by Competing Ferroelectric and Trap‐Assisted Switching in IGZO Transistors with Al2O3/HfO2 Dielectrics

Advanced Functional Materials, EarlyView.
A frequency‐tunable ferroelectric synaptic transistor based on a buried‐gate InGaZnO channel and Al2O3/HfO2 dielectric stack exhibits linear and reversible weight updates using single‐polarity pulses. By switching between ferroelectric and trap‐assisted modes depending on input frequency, the device simplifies neuromorphic circuit design and achieves ...
Ojun Kwon, Dong Ho Lee, Seyoung Oh, Jongwon Yoon, Hyo‐Bae Kim, Ji‐Hoon Ahn, Woojin Park, Han Seul Kim, Byungjin Cho   +8 more
wiley   +1 more source

Decreased Default Mode Network connectivity correlates with age-associated structural and cognitive changes [PDF]

, 2014
Ageing entails cognitive and motor decline as well as brain changes such as loss of gray (GM) and white matter (WM) integrity, neurovascular and functional connectivity alterations.
Arenaza-Urquijo, Eider Maria, Bargalló Alabart, Núria​, Bartrés Faz, David, Fernández-Cabello, Sara, Junqué i Plaja, Carme, 1955-, Ros Rahola, Emilio, Sala Llonch, Roser, Solana Díaz, Elisabeth, Valls Pedret, Cinta, Vidal Piñeiro, Dídac   +9 more
core   +2 more sources

The surprising role of the default mode network in naturalistic perception

Communications Biology, 2020
The default mode network (DMN) is a group of high-order brain regions recently implicated in processing external naturalistic events, yet it remains unclear what cognitive function it serves. Here we identified the cognitive states predictive of DMN fMRI
Talia Brandman, R. Malach, E. Simony
semanticscholar   +1 more source

Digital Discovery of Synthesizable Metal−Organic Frameworks via Molecular Dynamics‑Informed, High‑Fidelity Deep Learning

Advanced Functional Materials, EarlyView.
Tabular foundation model interrogates the synthetic likelihood of metal−organic frameworks. Abstract Metal–organic frameworks (MOFs) are celebrated for their chemical and structural versatility, and in‑silico screening has significantly accelerated their discovery; yet most hypothetical MOFs (hMOFs) never reach the bench because their synthetic ...
Xiaoyu Wu, Rui Zheng, Quan Liu, Jianwen Jiang   +3 more
wiley   +1 more source

Resting state networks: review and applications of an evolving concept

Iatreia, 2016
The concept of resting state networks refers to coherent fluctuations of brain activity, which appear when the subjects are not engaged in any task or superior cognitive process. Such networks have been identified in functional magnetic resonance studies
Arrubla, Jorge
doaj   +1 more source

Functional imaging evidence for task-induced deactivation and disconnection of a major default mode network hub in the mouse brain

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Our report first validates an imaging technique, functional ultrasound, an experimental approach providing significantly higher sensitivity and spatiotemporal resolution than fMRI, for the study of sensory stimulation-induced changes in ...
J. Ferrier, E. Tiran, T. Deffieux, M. Tanter, Z. Lenkei   +4 more
semanticscholar   +1 more source