Results 61 to 70 of about 91,262 (247)

Diferencias en las estadísticas e juego entre los equipos ganadores y perdedores de la Copa del Rey 2008 de balonmano masculino [Difference in the statistics of game between the winning and losing teams of the king’s cup 2008 of male handball]

open access: yesE-balonmano.com: Revista de Ciencias del Deporte, 2010
Resumen El objetivo de este estudio es analizar en que se diferencian los equipos ganadores y perdedores de la Copa del Rey 08 de balonmano masculino en función de las estadísticas de juego.
Francisco Javier Sáez Blázquez   +2 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Aceptar el veredicto del árbitro: el último reto de la democracia electoral en México

open access: yesRevista del Instituto Electoral del Estado de México. Apuntes Electorales, 2016
En este ensayo se describe la importancia para la democracia mexicana de fomentar en los candidatos un comportamiento ético durante las contiendas comiciales, sobre todo para que los que no obtengan la victoria acepten los resultados.
Carolina Varela-Martínez
doaj  

The Role of Infertility Stress and Defeat in Predicting the Quality of Infertile Women\'s Marital Relationship

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2021
Background and Objectives: Infertility is one of the bitter experiences of life that causes many psychological problems for the individual and his family.
Seyedeh Mohadeseh Rezaei   +2 more
doaj  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Defeat-induced activation of the ventral medial prefrontal cortex is necessary for resistance to conditioned defeat

open access: yes, 2013
The ventral medial prefrontal cortex (vmPFC) controls vulnerability to the negative effects of chronic or uncontrollable stress. Dominance status alters responses to social defeat in the conditioned defeat model, which is a model characterized by loss of
Morrison, Kathleen E   +7 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Social defeat stress induces myocardial injury by modulating inflammatory factors

open access: yesJournal of International Medical Research, 2020
Objectives We investigated the endoplasmic reticulum (ER) stress markers C/EBP homologous protein (CHOP) and glucose-regulated protein (GRP) 78, as well as the inflammatory factors nuclear factor (NF)-κB and IκBα, to assess how social defeat stress ...
XiaoLei Gao   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

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