Results 1 to 10 of about 1,902,450 (297)

Deciphering pathological behavior of pediatric medullary thyroid cancer from single-cell perspective [PDF]

open access: yesPeerJ, 2023
Background Pediatric medullary thyroid cancer (MTC) is one of the rare pediatric endocrine neoplasms. Derived from C cells of thyroid glands, MTC is more aggressive and more prompt to metastasis than other types of pediatric thyroid cancer. The mechanism
De-qian Chen   +10 more
doaj   +2 more sources

The Cellular and Molecular Landscape of Synchronous Pediatric Sialoblastoma and Hepatoblastoma

open access: yesFrontiers in Oncology, 2022
Sialoblastoma (SBL) is an infrequent embryonal malignant tumor originating from the salivary gland, resembling primitive salivary gland anlage, whereas hepatoblastoma (HB) is the most common pediatric liver malignancy. The simultaneous occurrence of both
Ran Yang   +16 more
doaj   +1 more source

ITRAQ-based proteomics analysis of human ectopic endometrial stromal cells treated by Maqian essential oil

open access: yesBMC Complementary Medicine and Therapies, 2023
Background Endometriosis is a common and complex syndrome characterized by the presence of endometrial-like tissue outside the uterus. Chinese medicine has been recently found to show good efficacy in treating endometriosis. Our previous results revealed
Liu-yang Zhang   +10 more
doaj   +1 more source

Research Progress of Estrogen Receptor in Ovarian Cancer

open access: yesClinical and Experimental Obstetrics & Gynecology, 2023
Objective: This review aims to provide some theoretical guidance for the precise treatment of ovarian cancer and the development of estrogen-related drugs.
Mengchen Zhang   +8 more
doaj   +1 more source

Molecular mechanism of Wilms’ tumor (Wt1) (+/−KTS) variants promoting proliferation and migration of ovarian epithelial cells by bioinformatics analysis

open access: yesJournal of Ovarian Research, 2023
Epithelial ovarian cancer (EOC) is a gynecological disease with the highest mortality. With the lack of understanding of its pathogenesis, no accurate early diagnosis and screening method has been established for EOC.
Xiaomei Wang   +7 more
doaj   +1 more source

DNA double-strand break genetic variants in patients with premature ovarian insufficiency

open access: yesJournal of Ovarian Research, 2023
Premature ovarian insufficiency (POI) is a clinically heterogeneous disease that may seriously affect the physical and mental health of women of reproductive age.
Xuechun Ding   +7 more
doaj   +1 more source

Concurrent newborn hearing and genetic screening of common hearing loss variants with bloodspot-based targeted next generation sequencing in Jiangxi province

open access: yesFrontiers in Pediatrics, 2022
Background and aimsConcurrent hearing and genetic screening of newborns have been widely adopted as an effective strategy in early diagnosis and intervention for hearing loss in many cities in China.
Haiyan Luo   +13 more
doaj   +1 more source

A local defect resonance for linear and nonlinear ultrasonic thermography [PDF]

open access: yes, 2014
An efficient wave-defect interaction is the key to a high thermal response of flaws in ultrasonic thermography. To selectively enhance defect vibrations a concept of local defect resonance is developed and applied to ultrasonic activation of defects ...
Solodov, I., Rahammer, M., Busse, G.
core   +1 more source

Untargeted Global Metabolomic Analysis Reveals the Mechanism of Tripropylamine-Enhanced Lycopene Accumulation in Blakeslea trispora

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
We previously determined that the cyclase inhibitor tripropylamine (TPA) significantly enhances lycopene accumulation in Blakeslea trispora. To elucidate the mechanism of TPA-enhanced lycopene accumulation, the untargeted metabolome of B.
Yanlong Wang   +8 more
doaj   +1 more source

Lycopene Aggravates Acute Gastric Injury Induced by Ethanol

open access: yesFrontiers in Nutrition, 2021
Lycopene is an important natural red pigment with strong singlet oxygen and peroxide free radical quenching ability. Ethanol directly destroys the epithelial cells of gastric mucosa, causing oxidative damage and inflammation.
Xin Chen   +9 more
doaj   +1 more source

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