Results 81 to 90 of about 508,402 (269)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

On the focal defect group of a block, characters of height zero, and lower defect group multiplicities

Journal of Algebra, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Symmetric group blocks of small defect

Journal of Algebra, 2004
This paper is an attempt to compute the decomposition numbers of the blocks of the symmetric group which have "small defect"; that is, blocks of weight smaller than the characteristic. We present various methods for computing such decomposition numbers and use these as support for a conjecture which relates decomposition numbers in different ...
James, Gordon, Mathas, Andrew
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Effect of Bone Morphogenetic Protein-2/Hydroxyapatite on Ankle Fusion with Bone Defect in an Rabbit Animal Model

Foot & Ankle Orthopaedics, 2018
Category: Basic Sciences/Biologics Introduction/Purpose: Revision arthrodesis surgery after total ankle arthroplasty failure has a problem related with large bone defect management after implant removal.
Kwang-Bok Lee MD, PhD, Le Hoang Nam Dang MD   +1 more
doaj   +1 more source

Blocks whose defect groups are Suzuki 2-groups

Journal of Algebra
We classify up to Morita equivalence all blocks whose defect groups are Suzuki $2$-groups. The classification holds for blocks over a suitable discrete valuation ring as well as for those over an algebraically closed field, and in fact holds up to basic Morita equivalence. As a consequence Donovan's conjecture holds for Suzuki $2$-groups.
openaire   +3 more sources

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Evaluation of the Repair of Bone Defect after Bone Marrow Stromal Cell Transplantation in Rat

Journal of Fasa University of Medical Sciences, 2013
Background & Objective: Bone marrow stromal cells (BMSCs) are multipotent stem cells that can proliferate and differentiate into osteogenic cells . T his study aimed to investigate the effects of BMSC transplantation for the repair of bone defects in the
Roghayeh Rezaei, Soheila Ebrahimi, Seyyed Homayoun Sadraie, Majid Naghdi, Giti Torkaman, Zabihollah Hasanzadeh, Gholamreza Kaka   +6 more
doaj