Results 101 to 110 of about 86,307 (298)
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
In recent years, efforts to promote energy conservation have become more active, and there is an increasing demand for high-efficiency motor coils. The efficiency of permanent magnet motors is closely related to manufacturing engineering.
Masato NAGANO +6 more
doaj +1 more source
Few-Shot Learning Based Balanced Distribution Adaptation for Heterogeneous Defect Prediction
Heterogeneous defect prediction (HDP) aims to predict the defect tendency of modules in one project using heterogeneous data collected from other projects.
Aili Wang +4 more
doaj +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Predicting Object Communication Errors in Constructor Development
An important challenge in dynamic software development is to predict object formation run-time object communication errors in complex environments involving multiple and multi-level object inheritance. This paper proposes a technique for doing so.
Abdul Majid Soomro +4 more
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Dealing with noise in defect prediction
Many software defect prediction models have been built using historical defect data obtained by mining software repositories (MSR). Recent studies have discovered that data so collected contain noises because current defect collection practices are based
Sunghun Kim +7 more
core +1 more source
Software testing is fundamental to ensuring the quality, reliability, and security of software systems. Over the past decade, artificial intelligence (AI) algorithms have been increasingly applied to automate testing processes, predict and detect defects,
Alex Escalante-Viteri, David Mauricio
doaj +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Defect prediction for Cascading Style Sheets
Testing is a crucial activity in software development. However exhaustive testing of a given software is impossible in practice because projects have serious time and budget limitations. Therefore, software testing teams need guidance about which modules
Diri, Banu, Bıcer, Serdar
core +1 more source

