Results 31 to 40 of about 442,351 (299)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
İstanbul Hukuk MecmuasıThe Product Liability Directive (PLD) 85/374 has been a significant aspect of European Union law for almost four decades, introducing strict liability for damages arising from defective products.
Ayşe Arat, Elif Akıncı
doaj +1 more source
Mathematics, 2023 Several industries are facing many challenges in their production systems due to increasing customer demand. Customer demand is growing for products with innovative features that are flexible, good quality, and appealing.
Baishakhi Ganguly +3 more
doaj +1 more source
Chatter, Clatter, and Blinks: Defective Car Alerts and the Role of Technological Advances in Design Defect/failure to Warn Cases [PDF]
, 2010 Car owners are familiar with the warning lights on the dashboard and the beeping sound reminding them to use their seatbelt. But, neither the legislature nor courts have concretely defined the legal nature of these alerts. This iBrief will analyze when a
McKell, James Forrest, Jr.
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Development risks: Definition under European Union law and justification for implementation in Serbian law [PDF]
Zbornik Radova: Pravni Fakultet u Novom Sadu, 2018 This paper analyses one of the most important and current issues related to the liability of the defective product producer, given that this form of liability has gained importance as a result of the development of consumer rights, the emphasis being on ...
Sekulić Miloš B.
doaj
“They Collected What Was Left of the Scraps”: Food Surplus as an Opportunity and Its Legal Incentives [PDF]
, 2013 For many years the problem of food security has been addressed only in relation to developing countries, due to the fact that people in developed nations had a relatively abundant supply of food.
Planchenstainer, Francesco
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Product recalls: The effects of industry, recall strategy and hazard, on shareholder wealth [PDF]
, 2018 The purpose of this paper is to provide insights into the effects of product recalls on shareholder wealth of manufacturing firms in different supply chains.
Bastl, Marko +3 more
core +1 more source