Results 41 to 50 of about 169,080 (262)

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Analyzing Crash Severity: Human Injury Severity Prediction Method Based on Transformer Model

Vehicles
Traffic accident-related injuries and fatalities are a serious global public health and social development challenge. The accurate prediction of crash severity improves road safety and reduces casualties, as well as serving road managers and policy ...
Yalan Jiang, Xianguo Qu, Weiwei Zhang, Wenfeng Guo, Jiejie Xu, Wangpengfei Yu, Yang Chen   +6 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

MODERN PRODUCT LIABILITY LAW JURIDICAL BASIS IN ISLAMIC LAW

Hamdard Islamicus, 2021
The term “Product liability” is used to identify the body of lawthat seeks to hold manufacturers and sellers financially responsiblefor their products not meeting safety standards.
MUHAMMAD AKBAR KHAN
doaj   +2 more sources

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Product liability in modern conditions: European reform experience

Цифровое право
At the end of September 2022, the European Commission presented two notable documents designed to fundamentally change the current system of product liability in Europe.
S. K. Stepanov
doaj   +1 more source

ANALISIS PENGENDALIAN KUALITAS PRODUK DI CV. BILO DATANG

Journal of Management Small and Medium Enterprises (SME's), 2020
The purpose of this study is to analyze the level and the type of damage in the production process CV.Bilo Datang and the solutions of quality control are carried out.
Aloysius Pansewidi, Ronald P C Fanggidae, Reyner F Makatita   +2 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Strict Liability Principle: Consumer Protection from Hidden Defective Products in Indonesia

Sriwijaya Law Review, 2020
Weak supervision on the standardization of the quality of goods products, the negative impact of the use of technology, and fraudulent products cause an increase in hidden defective goods products in the current era of globalization.
Holijah Holijah
doaj   +1 more source