Results 41 to 50 of about 2,909,995 (289)

Generic PLM system for SMEs: Application to an equipment manufacturer [PDF]

open access: yes, 2012
For several years, digital engineering has increasingly taken a more important place in the strategic issues of mechanical engineering companies.
Delplace, Jean-Charles   +4 more
core   +1 more source

Generalization of cut-in pre-crash scenarios for autonomous vehicles based on accident data

open access: yesScientific Reports
The utilization of high-risk test cases constitutes an effective approach to enhance the safety testing of autonomous vehicles (AVs) and enhance their efficiency.
Pingfei Li   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

An Assessment on Product Liability of Artificial Intelligence Producer

open access: yesİstanbul Hukuk Mecmuası
The increasing prevalence of artificial intelligence technologies brings with it several risks as well as many benefits. With the widespread use of artificial intelligence, the possibility of causing damage increases.
Uğur Karaca
doaj   +1 more source

Cost-Effective Imperfect Production-Inventory System under Variable Production Rate and Remanufacturing

open access: yesMathematics, 2023
Several industries are facing many challenges in their production systems due to increasing customer demand. Customer demand is growing for products with innovative features that are flexible, good quality, and appealing.
Baishakhi Ganguly   +3 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Analyzing Crash Severity: Human Injury Severity Prediction Method Based on Transformer Model

open access: yesVehicles
Traffic accident-related injuries and fatalities are a serious global public health and social development challenge. The accurate prediction of crash severity improves road safety and reduces casualties, as well as serving road managers and policy ...
Yalan Jiang   +6 more
doaj   +1 more source

Optimizing Defective Product Distribution for Sustainability and Profitability in Manufacturing Model under Neutrosophic Environment [PDF]

open access: yesNeutrosophic Sets and Systems
This study investigates the challenges associated with defective product distribution in manufacturing industries, contributing to environmental degradation, resource wastage, and financial losses.
B. Priskilla   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Liability for defective food product unprocessed and processed selected issues [PDF]

open access: yes, 2011
In accordance with food law liability for defective product is essential to seek damages, in the case of damage caused by the food. In the article the author presents several issues concerning liability for defective food product.
Wojciechowski, Paweł
core   +1 more source

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