Results 51 to 60 of about 444,038 (301)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Strikes, Scabs and Tread Separations: Labor Strife and the Production of Defective Bridgestone/Firestone Tires [PDF]

This paper provides a case study of the effect of labor relations on product quality. We consider whether a long, contentious strike and the hiring of permanent replacement workers by Bridgestone/Firestone in the mid-1990s contributed to the production ...
Alan B. Krueger, Alexandre Mas
core   +3 more sources

Analyzing Crash Severity: Human Injury Severity Prediction Method Based on Transformer Model

Vehicles
Traffic accident-related injuries and fatalities are a serious global public health and social development challenge. The accurate prediction of crash severity improves road safety and reduces casualties, as well as serving road managers and policy ...
Yalan Jiang, Xianguo Qu, Weiwei Zhang, Wenfeng Guo, Jiejie Xu, Wangpengfei Yu, Yang Chen   +6 more
doaj   +1 more source

ANALISIS PENGENDALIAN KUALITAS PRODUK DI CV. BILO DATANG

Journal of Management Small and Medium Enterprises (SME's), 2020
The purpose of this study is to analyze the level and the type of damage in the production process CV.Bilo Datang and the solutions of quality control are carried out.
Aloysius Pansewidi, Ronald P C Fanggidae, Reyner F Makatita   +2 more
doaj   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Strict Liability Principle: Consumer Protection from Hidden Defective Products in Indonesia

Sriwijaya Law Review, 2020
Weak supervision on the standardization of the quality of goods products, the negative impact of the use of technology, and fraudulent products cause an increase in hidden defective goods products in the current era of globalization.
Holijah Holijah
doaj   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Analisis Pengendalian Kualitas Statistik Injection Moulding Produk Cup Plastik Ø 80 Mm X 70 Mm [PDF]

, 2016
Plastic is used to make a wide range of products for example to tableware such as plates, cups, spoons and various other equipment. The advantages of this plastic material is resistant to corrosion, its density is low enough so that it can float, process
Puspitasari, E. (Etik)
core  

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Product liability in modern conditions: European reform experience

Цифровое право
At the end of September 2022, the European Commission presented two notable documents designed to fundamentally change the current system of product liability in Europe.
S. K. Stepanov
doaj   +1 more source