Results 91 to 100 of about 338,278 (318)

Reported Agonistic Behaviours in Domestic Horses Cluster According to Context

open access: yesAnimals
Agonistic behaviours are often directed at other animals for self-defence or to increase distance from valued resources, such as food. Examples include aggression and counter-predator behaviours.
Kate Fenner   +3 more
doaj   +1 more source

Finns’ opinions on foreign and security policy, national defence and security

open access: yes, 2021
A survey commissioned by the Advisory Board for Defence Information (ABDI) explored the opinions of Finnish people on Finnish foreign and security policy, defence policy and national defence.

core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Vietnam : une géopolitique en mutation au risque d’un dilemme stratégique ?

open access: yesMoussons, 2019
The rivalry between People’s Republic of China and Vietnam over the South China Sea highlights the profound changes Vietnam has experienced in its regional ambitions and geopolitical perceptions. These have been and remain fundamentally structured by its
Laurent Gédéon
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Prickly Defenders: A Review of Venomous Sea Urchins (Echinoidea)

open access: yesMarine Drugs
Sea urchins, Echinoidea, are widely known for their defensive spines and pedicellariae, with some species having co-evolved venom in conjunction with those appendages. Despite this, their venomous arsenal remains poorly understood.
Sina Ehlert-Flaskämper   +2 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Defence Physical Employment Standards Report. No. 4

open access: yes, 2005
Australian Defence Force (ADF) personnel, the ADF Chiefs of Service Committee (COSC) has endorsed a number of injury prevention strategies aimed at examining, analysing and evaluating injury-related risks and hazards within the ADF.
Sinclair, Wade   +5 more
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