Results 71 to 80 of about 431,850 (303)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Funding Australia's defence

open access: yes, 1983
Includes bibliographical referencesThis paper examines the attempt made between 1976 and 1983 to significantly raise expenditure on defence, and to direct a higher proportion of the total to the purchase of equipment.
Woolner, Derek
core  

Finns’ opinions on foreign and security policy, national defence and security

open access: yes, 2021
A survey commissioned by the Advisory Board for Defence Information (ABDI) explored the opinions of Finnish people on Finnish foreign and security policy, defence policy and national defence.

core   +1 more source

Effect of MgSO4 nutrition on Theobroma cacao L. susceptibility to Phytophthora megakarya infection

open access: yesPlant Protection Science, 2018
A new strategy to reduce the severity of black pod disease (BPD) in T. cacao plants using MgSO4 nutrition was investigated. The dynamics of the tolerance to BPD of 18 susceptible T.
Emile Minyaka   +7 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Defence diplomacy: is the game worth the candle? [PDF]

open access: yes, 2014
Few defence topics have been as prominent or invested with as much optimism in recent years as defence diplomacy. This paper has been created to explore the issue and help guide policymakers.
Hugh White   +6 more
core  

Arctic Security Strategies and the North Atlantic States

open access: yesArctic Review on Law and Politics, 2020
New uncertainties in international relations have presented several states in the West with important choices regarding their national strategies for the Arctic.
Njord Wegge
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Regulation of WRKY46 transcription factor function by mitogen-activated protein kinases in Arabidopsis thaliana.

open access: yesFrontiers in Plant Science, 2016
Mitogen-activated protein kinase (MAPK) cascades are central signalling pathways activated in plants after sensing internal developmental and external stress cues. Knowledge about the downstream substrate proteins of MAPKs is still limited in plants.
Arsheed Hussain Sheikh   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy